自拟养阴明目方熏蒸辅助玻切手术治疗糖尿病视网膜病变伴干眼症临床观察OA

Objective To investigate the clinical efficacy of self-made Yangyin Mingmu Formula fumigation-assisted vitrectomy in the treatment of diabetic retinopathy(DR)with dry eye,and its effect on the function of the tarsal gland.Methods From January 2023 to December 2024,100 patients with DR with dry eye who underwent vitrectomy in the hospital were selected and divided into the control group and the observation group by the random number table,with 50 cases in each group.The patients in the two groups were treated with Sodium Hyaluronate Eye Drops,and the patients in the observation group were additionally treated with self-made Yangyin Mingmu Formula fumigation.Both groups were treated continuously for 4 weeks.Results The total effective rate in the observation group was 98.00%,which was significantly higher than 86.00%in the control group(P＜0.05).After treatment,the secretion of meibomian glands,the degree of meibomian gland deficiency,and the Ocular Surface Disease Index Questionnaire(OSDI)scores in the two groups significantly decreased(P＜0.05),and the above scores in the observation group were significantly lower than those in the control group after 2 and 4 weeks of treatment(P＜0.05).No significant adverse reactions occurred in the two groups during the treatment.Conclusion Self-made Yangyin Mingmu Formula fumigation-assisted vitrectomy has clinical efficacy and safety in the treatment of DR with dry eye,which can improve the patients' meibomian gland function and ocular surface function.