急性缺血性卒中患者远程治疗的成本-效果分析及可支付性评价OA

Objective This study aims to evaluate the cost-effectiveness of telemedicine for patients with acute ischemic stroke and assess its affordability under given budget constraints,providing a quantitative basis for payment policy development and healthcare resource allocation.Methods A Markov model was constructed from payer's perspective to calculate the incremental cost-effectiveness ratio(ICER)of the telemedicine strategy for acute ischemic stroke patients over a lifetime horizon.One-way and probabilistic sensitivity analyses were performed.Affordability was assessed using affordability curve and cost-effectiveness affordability curve.Results The incremental cost of the telemedicine strategy was ¥1 475.431,the incremental quality-adjusted life-year(QALY)was 0.014,and the ICER was ¥105 387.929/QALY,falling below the threshold of three times the GDP per capita.Sensitivity analyses confirmed robustness of these findings.Affordability analysis showed that for a cohort of 100 000 patients,the strategy was not affordable at an annual budget below ¥44 million,but fully affordable at a budget of ¥327 million.Conclusions The telemedicine strategy is cost-effective for patients with acute ischemic stroke,supporting its broader adoption in clinical practice in China.