伦理与法律视角下医务人员对类器官及其技术应用的认知与态度研究OA
Study on the Cognition and Attitudes of Medical Personnel towards Organoids and Their Technological Applications from the Perspectives of Ethics and Law
目的:以医务人员为研究对象,旨在分析其对类器官及其技术应用中伦理和法律问题的认知与态度水平,并提出完善我国类器官等生物医学新技术治理的法治化路径.方法:采用方便抽样的方法,在吉林省4 个地区分别选取1～2 家二、三级医院的医务人员为研究对象,共获得有效问卷253 份.采用描述性统计、t 检验、方差分析、多元线性回归等方法分析医务人员对类器官及其技术应用的认知与态度水平及其差异.结果:医务人员对类器官及其技术应用的认知水平、态度倾向得分为(2.64±1.16)分、(4.35±0.76)分.多元线性回归分析结果显示,本人是否申请过伦理审查,所在医院有类器官及其技术的应用的伦理风险管理制度(培训、审查、风险管理等)是影响医务人员对类器官及其技术应用认知水平的影响因素(P<0.05);岗位、本人是否申请过伦理审查是影响医务人员对类器官及其技术应用态度倾向的影响因素(P<0.05).结论:医务人员对类器官及其技术应用的认知得分较低、态度得分较高,说明医务人员对其普遍持积极态度,但对类器官相关伦理及其法规认知仍存在不足,应通过强化伦理审查制度、完善知情同意程序、建立动态治理机制和公众参与体系,提高医务群体的法治意识与伦理敏感性,促进类器官及其技术应用等生物医学新技术的规范化发展.
Objective To analyze the healthcare professionals'awareness and attitudes toward ethical and legal issues in organoid technology applications,and propose legal pathways to improve governance of biomedical innovations like organoids in China.Meth-ods Convenience sampling method was used to recruit healthcare professionals from secondary and tertiary hospitals in four regions of Jilin Province.Descriptive statistics,t-tests,analysis of variance(ANOVA),and multiple linear regression were employed to ana-lyze the healthcare professionals'cognitive levels and attitudes toward organoids and their technological applications,as well as asso-ciated variations.Results The healthcare professionals scored(2.64±1.16)points for cognitive level and(4.35±0.76)points for attitudinal inclination toward organoids and their applications.Multivariate linear regression analysis revealed that having person-ally applied for ethical review and the presence of ethical risk management systems(training,review,risk management,etc.)for organoid technology applications within the hospital were significant factors influencing healthcare professionals'cognitive scores re-garding organoids and their applications(P<0.05).Additionally,job position and having personally applied for ethical review were factors significantly influencing healthcare professionals'attitude scores toward organoid technology applications(P<0.05).Conclu-sion Healthcare professionals demonstrated low cognitive scores and high attitude scores regarding organoid technology application,indicating a generally positive stance.However,their understanding of related ethical and regulatory frameworks remained inade-quate.It is suggested to strengthen ethical review systems,refine informed consent procedures,establish dynamic governance mecha-nisms and public participation systems to enhance the legal awareness and ethical sensitivity of the medical staff,which will promote the standardized development of organoid technology and other emerging biomedical technologies.
杨淑娟;许天怡;韩笑羽;翁艺炜;闫珊珊
吉林大学公共卫生学院,吉林 长春 130021吉林大学公共卫生学院,吉林 长春 130021吉林大学公共卫生学院,吉林 长春 130021吉林大学公共卫生学院,吉林 长春 130021吉林大学公共卫生学院,吉林 长春 130021
医药卫生
类器官知情同意伦理法律医务人员
organoidsinformed consentethicslawhealthcare professionals
《中国卫生事业管理》 2026 (5)
545-551,573,8
国家社会科学基金社科学术社团学术研究项目"积极老龄化背景下居家医疗的法律保障研究"(24SGC106)吉林省卫健委委托项目"吉林省2023年公立医院高质量发展指标完成情况调查"
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