血液退回情况分析及其影响因素探讨OA

Objective To analyze the situation of blood return in medical institutions in Qingdao,and provide a refer-ence basis for improving blood utilization efficiency.Methods Data on whole blood donations,and the distribution and re-turn of various blood components from 2022 to 2024 at the Qingdao Central Blood Station were collected.The overall trend of blood return,return situation of various blood components,main reasons for blood return,and related influencing factors were analyzed.Results The average blood return rate from 2022 to 2024 was 1.43‰(1 249/875 007),showing an over-all downward trend(P<0.05).The return rate of red blood cell(RBC)components increased year by year over the three years,while those of plasma components and cryoprecipitated antihemophilic factors decreased.Regarding the reasons for blood return,the return rates due to direct antiglobulin test(DAT)positivity and unexpected antibody positivity increased year by year,whereas those due to leakage and other reasons decreased.Univariate analysis of the causes of RBC compo-nents return showed that DAT positivity rates differed significantly by sex,age,and blood type,but not by donation season;unexpected antibody positivity rate differed significantly by sex,but not by age,blood type,or donation season.Multivari-ate analysis indicated that female gender,age>30 years,and blood type A or AB were independent risk factors for DAT pos-itivity,while female gender was an independent risk factor for unexpected antibody positivity.The return rate due to DAT positivity differed significantly among medical institutions of different levels,while that due to unexpected antibody positivity did not show a significant difference.Some donors who tested positive for DAT(76.92%,60/78)or unexpected antibody(71.15%,37/52)became antibody-negative upon subsequent donations.Comparing RBC donors with DAT positivity who became negative upon subsequent donations with those who remained positive,the difference in donation interval was statis-tically significant.Conclusion Over the past three years,the overall blood return rate in Qingdao has declined,but the re-turn rate of RBC components has increased.Further investigation and targeted interventions are needed to enhance the utili-zation of blood resources and ensure safe clinical blood transfusion.