造血干细胞移植并发胃肠道移植物抗宿主病管理的最佳证据总结OA

Objective To summarize the best evidence for the management of patients with gastrointestinal graft-versus-host disease after hematopoietic stem cell transplantation,and provide evidence-based references for clinical nursing work.Methods A systematic search was conducted for relevant evidence on the management of patients with gastrointestinal graft-versus-host disease after hematopoietic stem cell transplantation from domestic and foreign databases,as well as web-sites of blood and bone marrow transplantation related societies.The search period was from the establishment of the data-base until February 2026.Results After screening,a total of 19 articles were included,encompassing 3 clinical deci-sions,1 recommended practice,4 guidelines,7 expert consensuses,and 4 evidence summaries.Twenty-five pieces of best evidence were summarized across 8 aspects:multidisciplinary collaboration,influencing factors,assessment and monitoring,diagnostic differentiation,symptom management,dietary nutrition,medication guidance,and health education.Conclusion Summarizing the relevant evidence on the management of patients with gastrointestinal graft-versus-host disease after hem-atopoietic stem cell transplantation can provide evidence-based support for clinical medical staff,and it is recommended to apply it in combination with clinical practice and patient wishes.