人型支原体感染致硬膜下血肿:1例罕见病例报告OA
Subdural hematoma caused by Mycoplasma hominis infection:a rare case report
人型支原体(M.hominis)中枢神经系统(CNS)感染临床主要表现为脑炎、脑膜炎或脑脓肿,硬膜下血肿较为罕见,易导致误诊.本文报告1例32岁女性,剖宫产后出现发热、头痛及偏瘫,其影像学检查同时呈现硬膜下血肿与脑膜脑炎征象.通过脑脊液(CSF)宏基因组二代测序(mNGS)检出人型支原体而明确诊断,经针对性抗感染治疗后患者康复.本案例提示,对于无明显外伤出现硬膜下血肿的感染病例,需将人型支原体列为重要鉴别病原体,且 mNGS是明确此类诊断的关键技术.
Mycoplasma hominis(M.hominis)central nervous system(CNS)infection is mainly manifested clinically as encephalitis,meningitis or brain abscess,but the manifestation of subdural hematoma is rare,which can be easily misdiagnosed.This paper reports a case of a 32-year-old female who developed fever,headache,and hemiplegia after cesarean section.Imaging examination revealed both subdural hematoma and meningoencephalitis.The diagnosis was confirmed through detection of M.hominis by metagenomic next-generation sequencing(mNGS)of cerebrospinal fluid(CSF).After targeted anti-infective treatment,the patient recovered.This case suggests that for infection cases presenting with subdural hematoma without obvious trauma,M.hominis should be as an important differential pathogen,and mNGS is a key technique for clarifying such diagnosis.
马国梅;纪叶;王亚丽;韩敬哲
哈励逊国际和平医院 神经内科,河北 衡水 053000哈励逊国际和平医院 神经功能检查科,河北 衡水 053000哈励逊国际和平医院 神经内科,河北 衡水 053000哈励逊国际和平医院 神经内科,河北 衡水 053000
医药卫生
人型支原体中枢神经系统感染硬膜下血肿mNGS
M.hominiscentral nervous system infectionsubdural hematomamNGS
《中国感染控制杂志》 2026 (5)
767-769,3
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