原发性高嗜酸性粒细胞增多综合征致多发性急性脑梗死1例报告OA
Multiple acute cerebral infarctions caused by primary hypereosinophilic syndrome:A case report
原发性高嗜酸性粒细胞增多综合征表现为外周循环中的嗜酸性粒细胞克隆性增生>1.50×109/L并伴有其他组织器官损伤,目前国内关于该疾病导致脑梗死的病例报道较少.本文报道1例由该疾病引起的多发性急性脑梗死患者,以腹痛起病,伴有肌钙蛋白增高,后出现双侧的前、后循环区域多发性急性脑梗死,通过激素和伊马替尼治疗后临床症状得到明显改善.本报告旨在提高临床医生对高嗜酸性粒细胞增多综合征的警惕,尽早明确诊断并积极治疗改善预后.
Primary hypereosinophilic syndrome manifests as clonal proliferation of eosinophils(>1.50×109/L)in peripheral circulation,accompanied by damage to other tissues and organs,and at present,there are relatively few case reports on cerebral infarction caused by this disease in China.This article reports a case of multiple acute cerebral infarc-tions caused by this disease,in which the patient had abdominal pain as the initial presentation,accompanied by an in-crease in troponin.Then the patient developed multiple acute cerebral infarctions in the anterior and posterior circulation regions at both sides,and clinical symptoms were significantly improved after treatment with hormones and imatinib.This case report aims to improve the awareness of hypereosinophilic syndrome among clinicians.A confirmed diagnosis should be made as early as possible and treatment should be performed actively to improve prognosis.
王栋梁;王昊;张福青;张卓然;杜晨霄;杜艳芬;李新
天津医科大学第二医院神经内科,天津 300211天津医科大学第二医院神经内科,天津 300211天津医科大学第二医院神经内科,天津 300211天津医科大学总医院神经内科,天津 300052天津医科大学第二医院血液内科,天津 300211天津医科大学第二医院神经内科,天津 300211天津医科大学第二医院神经内科,天津 300211
医药卫生
高嗜酸性粒细胞增多综合征急性脑梗死伊马替尼
Hypereosinophilic syndromeAcute cerebral infarctionImatinib
《中风与神经疾病杂志》 2026 (5)
466-470,5
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