Development and validation of a static multiple light scattering(SMLS)method for real-time colloidal stability assessment in nanoparticle formulationsOA
Development and validation of a static multiple light scattering(SMLS)method for real-time colloidal stability assessment in nanoparticle formulations
Haiyang Shen;Shiqi Huang;Renjie Li;Hongliang Wang;Yanfang Yang;Yuling Liu;Jun Ye;Xiaohai Ma
Department of Interventional Diagnosis and Treatment,Beijing Anzhen Hospital,Capital Medical University,Beijing,100029,China||Department of Vascular Surgery,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing,100091,ChinaState Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences &Peking Union Medical College,Beijing,100050,China||Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation,Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing,100050,ChinaState Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences &Peking Union Medical College,Beijing,100050,China||Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation,Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing,100050,ChinaState Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences &Peking Union Medical College,Beijing,100050,China||Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation,Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing,100050,ChinaState Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences &Peking Union Medical College,Beijing,100050,China||Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation,Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing,100050,ChinaState Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences &Peking Union Medical College,Beijing,100050,China||Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation,Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing,100050,ChinaState Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences &Peking Union Medical College,Beijing,100050,China||Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation,Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing,100050,ChinaDepartment of Interventional Diagnosis and Treatment,Beijing Anzhen Hospital,Capital Medical University,Beijing,100029,China
Nanoparticle formulationsColloidal stabilityStatic multiple light scatteringDynamic light scatteringDrug delivery
Nanoparticle formulationsColloidal stabilityStatic multiple light scatteringDynamic light scatteringDrug delivery
《药物分析学报（英文）》 2026 (3)
708-722,15
This work was financially supported by the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sci-ences,China(Grant No.:2021-I2M-1-026),the National Natural Science Foundation of China(Grant No.:82304393),Beijing Natural Science Foundation,China(Grant No.:L242027),and the National Key Research and Development Program of China(Grant No.:2023YFC2706100).Scheme 1,Figs.2A,4A,7A,and 8A and Graphical abstract were drawn by using BioRender.com.
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