Synergistic cell membrane-coated ECL-DNA biosensor for specificity-enhanced drug lead evaluationOA
Synergistic cell membrane-coated ECL-DNA biosensor for specificity-enhanced drug lead evaluation
Dan Wu;Qi Hu;Qianhui Wu;Guoxi Xia;Jiabo Wang;Yusi Bu;Xiaoyu Xie;Sicen Wang
School of Pharmacy,Health Science Center,Xi'an Jiaotong University,Xi'an,710061,China||Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis,Xi'an,710061,ChinaSchool of Pharmacy,Health Science Center,Xi'an Jiaotong University,Xi'an,710061,China||Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis,Xi'an,710061,ChinaSchool of Pharmacy,Health Science Center,Xi'an Jiaotong University,Xi'an,710061,China||Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis,Xi'an,710061,ChinaSchool of Pharmacy,Health Science Center,Xi'an Jiaotong University,Xi'an,710061,China||Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis,Xi'an,710061,ChinaSchool of Pharmacy,Health Science Center,Xi'an Jiaotong University,Xi'an,710061,China||Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis,Xi'an,710061,ChinaSchool of Pharmacy,Health Science Center,Xi'an Jiaotong University,Xi'an,710061,China||Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis,Xi'an,710061,ChinaSchool of Pharmacy,Health Science Center,Xi'an Jiaotong University,Xi'an,710061,China||Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis,Xi'an,710061,China||Key Laboratory of Environment and Genes Related to Diseases(Xi'an Jiaotong University),Ministry of Education,Xi'an,710061,ChinaSchool of Pharmacy,Health Science Center,Xi'an Jiaotong University,Xi'an,710061,China||Shaanxi Engineering Research Center of Cardiovascular Drugs Screening & Analysis,Xi'an,710061,China
Cell membrane coating technologyAngiotensin-converting enzyme 2Drug lead evaluationElectrochemiluminescence biosensorAptamer
Cell membrane coating technologyAngiotensin-converting enzyme 2Drug lead evaluationElectrochemiluminescence biosensorAptamer
《药物分析学报（英文）》 2026 (2)
438-451,14
This work was supported by the National Natural Science Foundation of China(Grant Nos.:82273891 and 82373832),the Joint Funds of the National Natural Science Foundation of China(Grant No.:U24A20796),Xi'an Association for Science and Tech-nology Youth Talent Support Program,China(Program No.:959202313022),and Shaanxi Province Qin Chuangyuan"Scientists+Engineers"Team Construction,China(Grant No.:2022KXJ-168),Shaanxi Province TCM"Double Chain Integration"Young and Middle-aged Scientific Research Innovation Team,China(Grant No.:2022-SLRH-YQ-001).We thank Ms.Ying Hao from the Instrument Analysis Center of Xi'an Jiaotong University for her assistance with the bioimaging experiments.
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