Breaking the boundaries of affinity selection-mass spectrometry:From ligand screening to target-ligand interaction insightsOA
Breaking the boundaries of affinity selection-mass spectrometry:From ligand screening to target-ligand interaction insights
Bruno Sérgio do Amaral;Carmen Lucia Cardoso;Quezia Bezerra Cass;Marcela Cristina De Moraes
Federal Institute of Education,Science and Technology of São Paulo,São Paulo,05110-000,BrazilDepartment of Chemistry,Faculty of Philosophy,Sciences and Letters of Ribeirão Preto,University of São Paulo,Ribeirão Preto,14040-900,BrazilDepartment of Chemistry,Federal University of São Carlos,São Carlos,13565-905,BrazilDepartment of Organic Chemistry,Fluminense Federal University,Niterói,24020-007,Brazil
Affinity selection mass spectrometryCompetition assaysDrug discoveryFragment screeningKD determinationLigand-target interactionsMolecular glues
Affinity selection mass spectrometryCompetition assaysDrug discoveryFragment screeningKD determinationLigand-target interactionsMolecular glues
《药物分析学报（英文）》 2026 (2)
347-358,12
The authors acknowledge Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro(FAPERJ),Brazil(Grant Nos.:E-26/210.017/2024,E-200.172/2023,E-26/200.165/2024,E-26/200.164/2024,and E-26/210.547/2025),the Coordina-tion for the Improvement of Higher Education Personnel(CAPES),Brazil(Finance Code 001),and National Council for Scientific and Technological Development(CNPq),Brazil(Grant Nos.:307108/2021-0 and 302464/2022-0)for their support.All figures,including Graphical abstract,were created with BioRender.com.
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