首页|期刊导航|亚太传统医药|基于"脾为之卫"探讨中医治疗脾虚湿蕴型溃疡性结肠炎

基于"脾为之卫"探讨中医治疗脾虚湿蕴型溃疡性结肠炎OA

Exploring the Traditional Chinese Medicine Treatment of Ulcerative Colitis with Spleen Deficiency and Dampness Accumulation Based on"Spleen for the Defense"Theory

中文摘要英文摘要

基于"脾为之卫"理论,结合现代医学研究,探讨脾虚湿蕴型溃疡性结肠炎(Ulcerative colitis,UC)的发病机制及中医治疗策略.UC病机为本虚标实,其中脾气虚弱为发病之本、湿盛为标.脾气虚弱在病理过程中起主导作用,与湿盛互为因果,形成恶性循环,加剧病情.脾虚湿蕴证是 UC的主要证型,现代医学认为其主要的发病机制为肠道菌群紊乱、黏膜屏障损伤及免疫功能失衡等."脾为之卫"理论通过益气健脾、化湿和中治法治疗 UC,能显著改善患者临床症状,列举典型病案以证之.

Based on"Spleen for the Defense"theory and incorporating modern medical research,this study investigates the pathogenesis and traditional Chinese medicine(TCM)therapeutic strategies for ulcerative colitis(UC)with spleen deficiency and dampness accumulation syndrome.The disease mechanism of UC involves root deficiency with superficial excess,where spleen Qi deficiency serves as the fundamental cause of pathogenesis,while dampness abundance mani-fests as the secondary aspect.Spleen Qi deficiency plays a dominant role in the pathological process,forming a vicious cycle with dampness accumulation that exacerbates disease progression.The spleen deficiency with dampness accumu-lation pattern represents the primary syndrome type of UC,which modern medicine attributes to intestinal dysbiosis,mucosal barrier damage,and immune dysfunction.The"Spleen as the Defense"theory employs therapeutic approaches of replenishing Qi,fortifying the spleen,resolving dampness,and harmonizing the Middle Jiao to treat UC.Clinical case studies demonstrate that this treatment modality significantly improves patients'clinical symptoms.

刘姝雯;杨振斌

扬州大学,江苏 扬州 225009扬州市中医院,江苏 扬州 225002

医药卫生

溃疡性结肠炎脾虚湿蕴肠道菌群肠道黏膜屏障肠道免疫中医治疗

ulcerative colitisspleen deficiency and dampness accumulationgut microbiotaintestinal mucosal barrierintestinal immunitytraditional Chinese medicine treatment

《亚太传统医药》 2026 (6)

200-204,5

扬州市卫生健康委员会科研专项(2023-2-11)

10.11954/ytctyy.202606034

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