首页|期刊导航|协和医学杂志|人工智能驱动肺癌诊疗:研究进展与未来展望

人工智能驱动肺癌诊疗:研究进展与未来展望OA

Artificial Intelligence Drives Lung Cancer Diagnosis and Treatment:Research Progress and Future Prospects

中文摘要英文摘要

肺癌作为全球致死率最高的恶性肿瘤,其诊疗模式正经历从精准医学向智慧医学的范式跃迁.人工智能(artificial intelligence,AI)技术凭借其在多模态数据融合、高维特征提取等方面的核心优势,已深度渗透至肺癌筛查、诊断及个体化治疗的全生命周期,在改善患者临床结局与提升诊疗效率方面展现出显著价值,正在重塑肺癌诊疗底层逻辑与临床实践路径.本文阐述了 AI 在肺癌临床诊疗真实场景中的最新进展,重点梳理了多模态数据融合架构、AI 辅助肺癌诊疗的应用突破与临床转化所面临的现实障碍,批判性分析了数据标准化、隐私保护及伦理合规等核心挑战,最后展望了构建联邦学习驱动、数据要素赋能的全国性肺癌智慧诊疗生态系统未来图景,为 AI 在肺癌精准诊疗中的规范化应用与创新发展提供参考.

Lung cancer,the malignancy with the highest global mortality rate,is currently undergoing a paradigm shift from precision medicine to intelligent medicine in its diagnostic and therapeutic models.Arti-ficial intelligence(AI),leveraging its core advantages in multimodal data fusion and high-dimensional feature extraction,has deeply permeated the entire disease continuum of lung cancer screening,diagnosis,and indi-vidualized treatment.AI demonstrates significant value in improving patient outcomes and enhancing clinical ef-ficiency,thereby reshaping the fundamental logic and clinical practice pathways of lung cancer management.This article reviews the latest advances of AI in real-world clinical diagnosis and treatment scenarios for lung cancer,with a focus on multimodal data fusion architectures,breakthrough applications of AI-assisted lung cancer diagnosis and treatment,and the practical barriers to clinical translation.It critically analyzes core chal-lenges including data standardization,privacy protection,and ethical compliance.Finally,it envisions the fu-ture landscape of a nationwide intelligent ecosystem for lung cancer diagnosis and treatment—driven by federated learning and empowered by data elements—providing a reference for the standardized application and innovative development of AI in precision lung cancer care.

白晶;陈克终;王俊

北京大学未来技术学院,北京 100871北京大学人民医院,胸外科,北京 100044||北京大学人民医院,胸部肿瘤研究所,北京 100044||中国医学科学院早期非小细胞肺癌智能诊疗创新单元(2021RU002),北京 100044||北京大学临床医学高等研究院,北京 100191北京大学人民医院,胸外科,北京 100044||北京大学人民医院,胸部肿瘤研究所,北京 100044||中国医学科学院早期非小细胞肺癌智能诊疗创新单元(2021RU002),北京 100044

医药卫生

肺癌诊疗人工智能多模态数据融合精准肿瘤学

lung cancer diagnosis and treatmentartificial intelligencemultimodal data fusionprecision oncology

《协和医学杂志》 2026 (3)

597-606,10

国家自然科学基金(82525052,82388102,82450111)中国医学科学院医学与健康科技创新工程项目(2021-I2M-5-002)北京大学临床科学家培训计划(BMU2025PYJH001)北京大学人民医院科研与发展基金(RZG2024-02)北京大学"医学+X"先导计划-人工智能与医学发展专项(BMU2025YXXLHAIYX002)北京大学人民医院科研发展基金(RDX2024-07)雄安新区科技计划项目(XA202501102003K) National Natural Science Foundation of China(82525052,82388102,82450111)CAMS Medical and Health Science and Technology Innovation Project(2021-I2M-5-002)Peking University Clinical Scientist Training Program,supported by the Fundamental Research Funds for the Central Universities(BMU2025PYJH001)Peking University People's Hospital Re-search and Development Funds(RZG2024-02)Peking University Medicine plus X Pilot Program-Artificial Intelligence and Med-ical Development Initiative(BMU2025YXXLHAIYX002)Peking University People's Hospital Scientific Research Development Funds(RDX2024-07)S&T Program of Xiongan New Area(XA202501102003K)

10.12290/xhyxzz.2026-0154

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