首页|期刊导航|现代妇产科进展|妊娠期糖尿病产妇产后出血影响因素分析及风险预测模型建立

妊娠期糖尿病产妇产后出血影响因素分析及风险预测模型建立OA

Analysis of influencing factors and development of a risk prediction model for postpar-tum haemorrhage in women with gestational diabetes mellitus(GDM)

中文摘要英文摘要

目的:探讨妊娠期糖尿病(GDM)产妇产后出血的相关影响因素及风险预测模型的构建.方法:回顾性分析2023 年2 月至2025 年2 月在崇州市人民医院分娩的384例 GDM 产妇的临床资料,其中未发生产后出血的产妇287 例,发生产后出血97 例.采用多因素 logistic 回归分析探讨 GDM 产妇产后出血的影响因素,并运用受试者工作特征(ROC)曲线评估预测模型的预测价值.结果:二元 logistic 回归模型显示,本次分娩方式(剖宫产)、孕次(≥3 次)、合并子痫前期、胎膜早破、胎位异常、宫缩乏力、纤维蛋白原(FIB)、糖化血红蛋白(HbA1c)、D-二聚体(DD)、一氧化氮(NO)均为 GDM 产妇产后出血的影响因素(P<0.05).ROC 曲线分析显示,上述单一指标预测 GDM 产妇产后出血的曲线下面积(AUC)分别为0.614、0.601、0.584、0.604、0.611、0.614、0.694、0.632、0.721、0.739;而构建的风险预测模型预测 GDM 产妇产后出血的 AUC 为 0.947,灵敏度和特异度分别为0.866、0.926,预测效能显著高于单一指标(P<0.05).结论:本次分娩方式(剖宫产)、孕次(≥3 次)、合并子痫前期、胎膜早破、胎位异常、宫缩乏力、FIB、HbA1c、DD、NO均是 GDM 产妇产后出血的影响因素,基于上述指标构建的风险预测模型对 GDM 产妇产后出血具有较好的预测效能.

Objective:To investigate the influencing factors and development of a risk prediction model for postpartum haemorrhage in women with gestational diabetes mellitus(GDM).Methods:A retrospective analysis was conducted to collect clinical data of 384 cases of GDM mothers who gave birth in Chongzhou People's Hospital from February 2023 to Februar-y 2025,and they were divided into the non-hemorrhagic group(n=287)and the hemorrhagic group(n=97)according to the status of the occurrence of postpartum hemorrhage.Multifactori-al logistic regression analysis was applied to explore the factors affecting postpartum haemor-rhage in women with GDM,and the predictive value of the prediction model was established by establishing the receiver operating characteristic(ROC)curve analysis.Results:The binary lo-gistic regression model showed that the mode of this delivery(cesarean section),the number of pregnancies(≥3),combined preeclampsia,premature rupture of membranes,abnormal fetal position,weak contractions,FIB,HbA1c,DD,and NO were all influential factors for postpartum haemorrhage in women with GDM(P<0.05).ROC curve analysis showed that the AUCs of the above individual indicator for predicting postpartum haemorrhage in GDM mothers were 0.614,0.601,0.584,0.604,0.611,0.614,0.694,0.632,0.721,and 0.739,respectively.The AUC of the prediction model for predicting postpartum haemorrhage in women with GDM was 0.947,and the sensitivity and specificity were 0.866,0.926.The AUC of the prediction model for pre-dicting postpartum haemorrhage in women with GDM was significantly higher than that of indi-vidual indicators(P<0.05).Conclusion:Mode of delivery(cesarean section),number of preg-nancies(≥3),preeclampsia,premature rupture of membranes,abnormal fetal position,contrac-tion weakness,FIB,HbA1c,DD,and NO were the factors influencing postpartum haemorrhage in women with GDM,and the risk prediction model based on the above indexes was more effec-tive in predicting postpartum haemorrhage in women with GDM.

龚琴;石敏;陈徐

崇州市人民医院,成都 611230崇州市人民医院,成都 611230崇州市人民医院,成都 611230

医药卫生

妊娠期糖尿病产妇产后出血影响因素预测模型价值

Gestational diabetes mellitus(GDM)MaternityPostpartum haemor-rhageInfluencing factorsPrediction modelValue

《现代妇产科进展》 2026 (5)

348-352,356,6

10.13283/j.cnki.xdfckjz.2026.05.003

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