hMPV M2-2 protein modulates host mRNA alternative splicing to favor virus replicationOA
hMPV M2-2 protein modulates host mRNA alternative splicing to favor virus replication
Jiayin Guo;Xiaojuan Jia;Miaowei Mao;Lishu Zheng;Ke Zhang;Yiman Huang;Pengtao Jiao;Dongqi Xie;Gang Pang;Jiaxu Ying;Qianru Yang;Ying Wu;Siqi Wang
Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai,China||University of Chinese Academy of Sciences,Beijing,China||Shanghai Institute of Immunity and Infection,Chinese Academy of Sciences,Shanghai,ChinaCAS Key Laboratory of Pathogen Microbiology and Immunology,Institute of Microbiology,Chinese Academy of Sciences,Beijing,ChinaShanghai Institute of Immunity and Infection,Chinese Academy of Sciences,Shanghai,China||Department of Ophthalmology,Eye & ENT Hospital,State Key Laboratory of Brain Function and Disorders,MOE Frontiers Center for Brain Science,Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases,Fudan University,Shanghai,ChinaNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing,China||NHC Key Laboratory of Medical Virology and Viral Diseases,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing,ChinaShanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai,China||Shanghai Institute of Immunity and Infection,Chinese Academy of Sciences,Shanghai,ChinaNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing,China||NHC Key Laboratory of Medical Virology and Viral Diseases,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing,ChinaInstitute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing,ChinaDepartment of Cell Biology,University of Texas Southwestern Medical Center,Texas,USAShanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai,China||University of Chinese Academy of Sciences,Beijing,China||Shanghai Institute of Immunity and Infection,Chinese Academy of Sciences,Shanghai,ChinaShanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai,China||University of Chinese Academy of Sciences,Beijing,China||Shanghai Institute of Immunity and Infection,Chinese Academy of Sciences,Shanghai,ChinaSchool of Life Sciences,Department of Biotechnology,Fudan University,Shanghai,ChinaKey Laboratory of Allergy and Immunology,Institute of Medical Virology,TaiKang Medical School(School of Basic Medical Sciences),Wuhan University,Hubei,ChinaUniversity of Chinese Academy of Sciences,Beijing,China||CAS Key Laboratory of Computational Biology,Shanghai Institute of Nutrition and Health,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Shanghai,China
human metapneumovirus(hMPV)mRNA splicingM2-2STRAPTANC2
human metapneumovirus(hMPV)mRNA splicingM2-2STRAPTANC2
《微生物与宿主健康（英文）》 2026 (6)
369-388,20
We thank Professor Rong Zhang from Fudan University for kindly providing the human metapneumovirus(hMPV)genomic plasmid.This work was funded by the Shanghai Pujiang Pro-gram(grant number 22PJ1414600 to K.Z.),the National Natural Science Foundation of China(grant numbers 82372224,82341052,and 82241078 to K.Z.,and 32471511 to M.M.),the Science and Technology Commission of Shanghai Munici-pality(grant number 24ZR1476500 to M.M.),and the Bill & Me-linda Gates Foundation(BMGF)-National Natural Science Foun-dation of China(NSFC)Joint Project on Vaccine Research and Development(grant numbers W2412022 and 2024VTJP1001 to M.M.).
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