基于营养风险评估的个体化营养支持对食管癌术后辅助化疗患者营养指标和免疫水平的影响OA

Objective To explore the impact of individualized nutritional support based on nutritional risk assessment on the nutritional indicators and immune levels of esophageal cancer patients undergoing postoperative adjuvant chemotherapy.Methods A total of 120 esophageal cancer patients with postoperative adjuvant chemotherapy in Shanghai Chest Hospital from January to October 2024 were se-lected and studied by convenience sampling method.They were divided into the control group and the observation group through random number table method,with 60 cases in each group.The control group received routine nutritional support treatment,while the observation group received individualized nutritional support treatment based on nutritional risk assessment.The changes of nutritional indicators including body mass index(BMI),serum albumin(ALB),and hemoglobin(Hb),immune levels including serum CD3+,CD4+,and CD4+/CD8+,and the quality of life before and after the intervention,and adverse reactions during the intervention were compared between the two groups.Results The levels of all nutritional indicators,the scores of the functional components of the quality of life scale QLQ-C30,and the immune levels were not significantly different between the two groups before the intervention(all P>0.05),were all increased in both groups after the intervention(all P<0.05),and the increases in the observation group were all more obvious than those in the control group(all P<0.05).During the intervention,the incidences of adverse reactions in the observation group were all lower than those in the control group(all P<0.05).Conclusions The implementation of individualized nutritional support therapy based on nutritional risk assessment can effectively improve the nutritional indicators of patients,enhance the quality of life and immune function,and reduce the risk of adverse reactions in esophageal cancer patients undergoing postoperative adjuvant chemotherapy.