新疆维吾尔自治区塔城地区住院早产儿出生后维生素D水平调查及影响因素分析OA

Objective:To investigate the postnatal vitamin D levels in hospitalized preterm infants in Tacheng prefecture,Xinjiang Uygur Autonomous Region,and analyze the influencing factors,so as to provide evidence for the prevention and treatment of vitamin D deficiency in preterm infants.Methods:A total of 140 preterm infants hospitalized in the Department of Neonatology of People's Hospital of Tacheng prefecture from Jan 2022 to Jun 2024 were selected as the research subjects.Serum 25-hydroxyvitamin D levels were detected using microparticle chemiluminescence assay.And its influencing factor was analyzed using univariate analysis and binary logistic regression.Results:The mean 25-hydroxyvitamin D level of the 140 preterm infants was(22.83±8.85)ng/ml,with 18 cases(12.86%)showing vitamin D deficiency,50 cases(35.71%)having vitamin D insufficiency,and 72 cases(51.43%)achieving adequate levels.Maternal factors including lack of vitamin D supplementation during pregnancy or supplementation for less than 3 months,daily sun exposure time＜30 min,as well as infant factors including gestational age＜32 weeks,birth weight＜1 500 g,and birth during winter or spring,were identified as influencing factors for vitamin D deficiency/insufficiency in preterm infants after birth(P＜0.05).Conclusions:Vitamin D deficiency and insufficiency are common among preterm infants in the Tacheng prefecture,especially among those with gestational age＜32 weeks,birth weight＜1 500 g,born in winter and spring,whose mothers did not regularly supplement vitamin D during pregnancy or had sun exposure time＜30 min.Particular attention should be paid to perinatal vitamin D supplementation in preterm infants.