上海首例输入性寨卡病毒病病例处置OA

[Objective]To describe the disposal process of the first imported case of Zika virus disease in Shanghai,and to provide a reference for the prevention and control of imported infectious diseases in the future.[Methods]A retrospective review was conducted of the process by which epidemiological investigation,etiological testing,and case management were performed by the Shanghai municipal-and district-level Centers for Disease Control and Prevention(CDC)after one imported case of Zika virus disease was identified by Shanghai Customs.[Results]On April 8th,2025,customs authority at a certain airport in Shanghai identified a febrile inbound case(case A,female,40 years old).An antecubital venous blood specimen was obtained and analyzed by nucleic acid testing for various vector-borne pathogens,by which Zika virus nucleic acid was found to be positive.On 9 April,the district CDC collected antecubital venous blood specimens again from Case A and her three accompanying travelers(B,C,and D),and nucleic acid testing was conducted for multiple mosquito-borne infectious diseases.Case A again tested positive for Zika virus nucleic acid,while Traveler D(male,aged 6 years)tested positive for dengue virus nucleic acid.The other two travelers tested negative.Case A and Traveler D were subsequently transferred to a designated district hospital for isolation and treatment.After discharge,both cases left China and returned to their overseas residence.[Conclusion]Case A was the first imported case of Zika virus disease in Shanghai.For cases with a history of living in endemic areas of multiple infectious diseases such as dengue virus,Zika virus and chikungunya virus,it is necessary to carry out rapid testing of multiple pathogens simultaneously to prevent missed diagnosis or misdiagnosis.