实时动态血糖监测在糖尿病肾病血液透析患者优化治疗指导中的应用价值OA

Objective To explore the application value of real-time continuous glucose monitoring(CGM)in the optimiza-tion of treatment guidance for patients with diabetic kidney disease(DKD)undergoing hemodialysis.Methods A total of 60 patients with DKD on hemodialysis admitted to Longhua District People's Hospital from November 2019 to December 2023 were selected as the research objects.According to the random number table method,they were divided into the observation group and the control group,with 30 cases in each group.The observation group received real-time CGM,while the control group received finger blood glucose monitoring.The blood glucose control status,renal function indicators,self-management situation of the two groups were compared,and the occurrence of complications during the monitoring period was statistically analyzed.Results The average duration of hyperglycemia in the observation group was shorter than that in the control group,and the average range of blood glucose fluctuations was smaller than that in the control group,the differences were statistically significant(P＜0.05).After 14 days of monitoring,the levels of fasting plasma glucose(FPG),2 hour postprandi-al plasma glucose(2 h PG),glycated haemoglobin(HbAlc),24 hour urinary total protein(24 h UTP),blood urea nitrogen(BUN),and serum creatinine(SCr)were lower in the observation group than in the control group,and the differences were statistically significant(P＜0.05).After 14 days of monitoring,the scores of the summary of diabetes self-care activities(SDSCA)in both groups was higher than those before monitoring,while the scores of the Chinese version hypoglycemia fear surveyll-worry scale(CHFS Ⅱ-WS)were lower than those before monitoring,the SDSCA score in the observation group was higher than that in the control group,and the CHFS Ⅱ-WS score was lower than that in the control group,and the differ-ences were statistically significant(P＜0.05).There was no statistically significant difference in the total incidence of com-plications between the two groups(P＞0.05).Conclusion The application of real-time CGM technology in DKD hemodialy-sis patients can effectively improve the effect of blood glucose control,reduce blood glucose fluctuations in patients,shorten the duration of hyperglycemia,protect renal function,enhance patients' self-management ability and alleviate the fear of hy-poglycemia.