合并亚临床甲状腺功能减退的脑梗死临床特点及影响因素OA

Objective To analyze the clinical characteristics of arteriosclerotic cerebral infarction(ASCI)complicated with subclinical hypothyroidism(SCH),and explore its influencing factors.Methods This retrospective study collected clinical data from ASCI patients admitted to the Department of Neurology,Beijing Tongren Hospital,Capital Medical University between January 1,2020 and August 1,2022.The propensity score matching method was used to analyze the clinical characteristics of ASCI patients complicated with SCH,and univariate and multivariate Logistic regression were applied to explore its influencing factors.Results The SCH group had significantly lower rates of hypertension(74.36%vs 93.91%,P<0.001),hyperlipidemia(15.38%vs 85.28%,P<0.001),and hyperhomocysteinemia(5.13%vs 20.30%,P<0.001)compared to the non-SCH group.C-reactive protein(OR=0.735,95%CI:0.572-0.924,P=0.011),neutrophils(OR=1.964,95%CI:1.263-3.210,P=0.004),hypertension(OR=0.178,95%CI:0.042-0.722,P=0.016),and hyperlipidemia(OR=0.021,95%CI:0.006-0.062,P<0.001)as influencing factors for ASCI complicated with SCH.Conclusion C-reactive protein,neutrophils,hypertension,and hyperlipidemia may be influencing factors for ASCI complicated with SCH.