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基于AME-MoE模型的微生物浓度检验方法OA

Microbial Concentration Testing Method Based on the AME-MoE Model

中文摘要英文摘要

为解决传统微生物浓度检验方法滞后性强、成本高、可解释性差的问题,提出基于人工微生物生态系统与混合专家(artificial microbial ecosystem and mixture-of-experts,AME-MoE)模型的微生物浓度检验方法.该模型将复杂的微生物群落动态分解为由多个轻量化专家子模型分别建模的特定菌种响应,并引入变换器(Transformer)增强模型对非线性关系的捕捉能力,最终生成微生物浓度检验结果.研究表明,参考菌落形成单位(colony forming unit,CFU),AME-MoE 模型的均方根误差低至 0.15lg(CFU/g),代谢通量检验准确率达到 88.7%;同时,单样本推理延迟时间仅为22 ms,且在数据稀缺和存在噪声的场景中表现出优异的泛化能力.AME-MoE 模型实现高精度、低延迟、强泛化的微生物浓度智能检验,能够为医院感染控制、食品安全、环境微生物风险实时监测提供具备实际应用价值的决策工具.

To address the issues of strong lag,high cost,and poor interpretability in traditional microbial concentration test methods,a new method of microbial concentration test based on an artificial microbial ecosystem and mixture-of-experts(AME-MoE)model was proposed.The model decomposed dynamically the complex microbial communities into specific bacterial species response modeled by multiple lightweight expert submodels,and introduced a Transformer to enhance the model's capture of nonlinear relationships,ultimately generating microbial concentration detection results.The research demonstrated that,referring to colony forming unit(CFU),the root mean square error of AME-MoE model was as low as 0.15lg(CFU/g),with a metabolic flux detection accuracy of 88.7%.Additionally,the single-sample inference latency time was only 22 ms,and the model exhibited excellent generalization capabilities in scenarios with data scarcity and in a noisy environment.AME-MoE model achieved high-precision,low-latency,and strongly generalizable microbial concentration intelligent detection,providing a decision-making tool with practical application value for hospital infection control,food safety,and real-time monitoring of environmental microbial risks.

张贤;徐建飞

安徽卫生健康职业学院 医疗卫生技术系,安徽 池州 247100芜湖学院 智能制造学院,安徽 芜湖 241000

信息技术与安全科学

人工微生物生态系统混合专家系统微生物浓度检验模型优化智能决策

artificial microbial ecosystemmixture-of-expert systemmicrobial concentration inspectionmodel optimizationintelligent decision-making

《湖北民族大学学报(自然科学版)》 2026 (2)

228-233,6

安徽省教学研究项目(2022jyxm619).

10.13501/j.cnki.42-1908/n.2026.06.007

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