首页|期刊导航|广州中医药大学学报|腕踝针联合西药治疗急性腰椎间盘突出症的疗效观察

腕踝针联合西药治疗急性腰椎间盘突出症的疗效观察OA

Observation on the Efficacy of Wrist-Ankle Acupuncture Combined with Western Medicine in the Treatment of Acute Lumbar Disc Herniation

中文摘要英文摘要

[目的]观察腕踝针联合西药治疗急性腰椎间盘突出症的临床疗效.[方法]选取2025年1月至2025年6月在佛山市中医院疼痛科、推拿科收治的116例明确诊断为急性腰椎间盘突出症的患者为研究对象.采用随机数字表法将患者随机分为观察组和对照组,每组各58例.对照组给予西医常规治疗,观察组在对照组治疗的基础上,给予腕踝针治疗.连续治疗2周.治疗2周后,评价2组临床疗效.观察2组患者治疗前后简化McGill疼痛量表(SF-MPQ)评分、日本骨科协会(JOA)评分和Oswestry功能障碍指数(ODI)评分的变化情况,以及腰椎前屈、后伸、左右侧屈的最大活动角度的情况,检测L4-5水平竖脊肌的屈曲过程平均肌电值(AEMG)、伸直过程AEMG及屈伸松弛比(FRR).比较2组患者治疗前后前列腺素E2(PGE2)、P物质(SP)、5-羟色胺(5-HT)、白细胞介素1β(IL-1β)、肿瘤坏死因子α(TNF-α)、白细胞介素6(IL-6)水平以及基质金属蛋白酶(MMPs)和金属蛋白酶组织抑制因子(TIMPs)水平的变化情况.[结果](1)观察组总有效率为94.83%(55/58),对照组为82.76%(48/58).观察组疗效优于对照组,差异有统计学意义(P<0.05).(2)治疗后,2组患者的JOA评分、ODI评分及SF-MPQ评分均明显改善(P<0.05),且观察组在改善JOA评分、ODI评分及SF-MPQ评分方面明显优于对照组,差异有统计学意义(P<0.05).(3)治疗后,2组患者屈曲AEMG、伸直AEMG、FRR均明显改善(P<0.05),且观察组在改善屈曲AEMG、伸直AEMG、FRR方面明显优于对照组,差异有统计学意义(P<0.05).(4)治疗后,2组患者前屈、后伸、侧屈活动度均明显改善(P<0.05),且观察组在改善前屈、后伸、侧屈活动度方面明显优于对照组,差异有统计学意义(P<0.05).(5)治疗后,2组患者血清PGE2、SP、5-HT水平均明显改善(P<0.05),且观察组在改善血清PGE2、SP、5-HT水平方面明显优于对照组,差异有统计学意义(P<0.05).(6)治疗后,2组患者血清IL-1β、TNF-α、IL-6、MMPs、TIMPs水平均明显改善(P<0.05),且观察组在改善血清IL-1β、TNF-α、IL-6、MMPs、TIMPs水平方面明显优于对照组,差异有统计学意义(P<0.05).[结论]腕踝针联合西药治疗急性腰椎间盘突出症,能够有效地缓解患者的疼痛症状,改善患者的腰椎功能与活动度,调节疼痛介质和炎症因子水平,纠正MMPs/TIMPs失衡,恢复腰背肌正常肌电活动,疗效确切.

Objective To observe the clinical efficacy of wrist-ankle acupuncture combined with western medicine in the treatment of acute lumbar disc herniation.Methods A total of 116 patients diagnosed with acute lumbar disc herniation admitted to the Department of Pain Medicine and the Department of Tuina at Foshan Hospital of Traditional Chinese Medicine from January 2025 to June 2025 were selected as study subjects.The patients were randomly divided into an observation group and a control group using a random number table method,with 58 cases in each group.The control group received conventional western medicine treatment,while the observation group received wrist-ankle acupuncture in addition to the treatment given to the control group.Both groups were treated continuously for 2 weeks.After 2 weeks of treatment,clinical efficacy was evaluated in both groups.Changes in the Short-Form McGill Pain Questionnaire(SF-MPQ)score,Japanese Orthopaedic Association(JOA)score,and Oswestry Disability Index(ODI)score were observed before and after treatment,as well as the maximum range of motion for lumbar flexion,extension,and lateral flexion.The average electromyography(AEMG)values during the flexion process,extension process,and flexion-relaxation ratio(FRR)of the erector spinae muscle at the L4-5 level were measured.Changes in serum levels of prostaglandin E2(PGE2),substance P(SP),5-hydroxytryptamine(5-HT),interleukin-1β(IL-1β),tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),matrix metalloproteinases(MMPs),and tissue inhibitors of metalloproteinases(TIMPs)were compared between the two groups before and after treatment.Results(1)The total effective rate was 94.83%(55/58)in the observation group and 82.76%(48/58)in the control group,with the observation group showing significantly better efficacy than the control group,the difference being statistically significant(P<0.05).(2)After treatment,JOA scores,ODI scores,and SF-MPQ scores were significantly improved in both groups(P<0.05),and the observation group demonstrated significantly greater improvements in JOA scores,ODI scores,and SF-MPQ scores compared with the control group,the difference being statistically significant(P<0.05).(3)After treatment,flexion AEMG,extension AEMG,and FRR were significantly improved in both groups(P<0.05),and the observation group showed significantly greater improvements in flexion AEMG,extension AEMG,and FRR compared with the control group,the difference being statistically significant(P<0.05).(4)After treatment,ranges of motion for flexion,extension,and lateral flexion were significantly improved in both groups(P<0.05),and the observation group demonstrated significantly greater improvements in flexion,extension,and lateral flexion ranges of motion compared with the control group,the difference being statistically significant(P<0.05).(5)After treatment,serum levels of PGE2,SP,and 5-HT were significantly improved in both groups(P<0.05),and the observation group,the difference being statistically significant showed significantly greater improvements in serum levels of PGE2,SP,and 5-HT compared with the control group(P<0.05).(6)After treatment,serum levels of IL-1β,TNF-α,IL-6,MMPs,and TIMPs were significantly improved in both groups(P<0.05),and the observation group demonstrated significantly greater improvements in serum levels of IL-1β,TNF-α,IL-6,MMPs,and TIMPs compared with the control group,the difference being statistically significant(P<0.05).Conclusion Wrist-ankle acupuncture combined with western medicine in the treatment of acute lumbar disc herniation can effectively alleviate pain symptoms,improve lumbar function and range of motion,regulate pain mediator and inflammatory factor levels,correct the MMPs/TIMPs imbalance,and restore normal electromyographic activity of the back muscles,demonstrating definite therapeutic efficacy.

邓玉婷;林敏如;何巧萍;林悦平;胡敏琪;敬娜;胡瑶;蔡惠铃;蔡海荣;黄金悦

广州中医药大学第八临床医学院,广东 佛山 528000||佛山市中医院,广东 佛山 528000广州中医药大学第二附属医院,广东 广州 510102广州中医药大学第八临床医学院,广东 佛山 528000||佛山市中医院,广东 佛山 528000广州中医药大学第八临床医学院,广东 佛山 528000||佛山市中医院,广东 佛山 528000广州中医药大学第八临床医学院,广东 佛山 528000||佛山市中医院,广东 佛山 528000广州中医药大学第八临床医学院,广东 佛山 528000||佛山市中医院,广东 佛山 528000广州中医药大学第二附属医院,广东 广州 510102广州中医药大学第二附属医院,广东 广州 510102广州中医药大学第二附属医院,广东 广州 510102广州中医药大学第二附属医院,广东 广州 510102

医药卫生

腕踝针急性腰椎间盘突出症腰椎功能疼痛介质炎症因子临床观察

wrist-ankle acupunctureacute lumbar disc herniationlumbar functionpain mediatorsinflammatory factorsclinical observation

《广州中医药大学学报》 2026 (6)

1562-1570,9

广东省中医药局科研资助项目(编号:2025113520233019)广东省科技厅科技计划资助项目(编号:2014A020221025)广州市科技计划资助项目(编号:2024A04J3302)佛山市卫生健康局资助项目(编号:20230108)

10.13359/j.cnki.gzxbtcm.2026.06.018

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