基于整合皮肤性病学理念探究治疗银屑病的中药药理与临床应用OA
Investigation into the Pharmacology and Clinical Use of Chinese Herbal Medicine for Psoriasis:An Integrated Dermatovenereology Perspective
基于阐述整合医学及整合皮肤性病学的内涵与发展,强调其突破专科细化局限、整合多学科资源与因素的核心价值,综述银屑病的研究进展,包括脂质代谢异常、CD147基因作用、相关致病基因发现及致病因子等机制的研究成果,进而深入分析中医药与整合皮肤性病学的内在契合性,介绍乳香、落新妇苷等中药活性成分在银屑病治疗中的作用及机制,梳理中药归经理论、药效与治法等药理研究基础,探讨中药与现代医学的整合应用路径,包括基础与临床、宏观与微观的整合,以及联合用药策略等.目前,中医药凭借多靶点、多层次的整体调节特性,在银屑病"未病先防""既病防变""瘥后防复"中具有独特优势,而基于整合皮肤性病学理念,推动中医药与现代医学的深度融合,是未来银屑病诊疗研究的重要方向.
This article elaborates on the connotation and development of integrated medicine and integrated dermatovenereology,emphasizing their core value in breaking through the limitations of subspecialty fragmentation and integrating multidisciplinary resources and factors.It reviews the research progress in psoriasis,including findings on lipid metabolism abnormalities,the role of CD147 gene,discovery of related pathogenic genes,and pathogenic factors.On this basis,it analyzes the intrinsic compatibility between traditional Chinese medicine(TCM)and integrated dermatovenereology.Furthermore,it introduces the therapeutic effects and mechanisms of active components of Chinese herbal medicine,such as boswellic acid and astilbin,in the treatment of psoriasis.The review also summarizes the pharmacological basis of TCM,including meridian tropism theory,efficacy,and therapeutic principles,and explores the integrated application pathways of TCM and modern medicine,encompassing the integration of basic research and clinical practice,macro and micro perspectives,as well as combination drug strategies.At present,TCM,with its multi-target,multi-level holistic regulatory characteristics,offers unique advantages in the prevention of psoriasis before its onset,intervention to prevent its progression,and management to prevent recurrence after remission.Grounded in the concept of integrated dermatovenereology,promoting the deep integration of TCM and modern medicine represents an important direction for future research on the diagnosis and treatment of psoriasis.
蒙军;王笳
四川文理学院,四川 达州 635000四川省中医药科学院,四川 成都 610041
医药卫生
银屑病整合皮肤性病学中药药理综述
psoriasisintegrated dermatovenereologypharmacology of Chinese herbal medicinereview
《西部中医药》 2026 (6)
38-43,6
皮肤病学教育部重点实验室(安徽医科大学)开放课题基金项目(AYPYS2024-22)四川中医药大健康产业发展与乡村振兴研究中心重点项目(DJKZD202305)四川文理学院横向科研项目(2025HX182).
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