内镜逆行胰胆管造影术中要重视十二指肠乳头的保护OA
Pay attention to the protection of duodenal papilla during endoscopic retrograde cholangiopancreatography
内镜逆行胰胆管造影(ERCP)是治疗胆总管结石、胆管狭窄、胆漏等疾病的首选方案之一.内镜下乳头括约肌切开(EST)及内镜下乳头球囊扩张(EPBD)可以降低取石的难度、提高结石的取净率.但EST及内镜下乳头大球囊扩张(EPLBD)会损伤Oddi括约肌,引发反流性胆管炎、结石复发等远期并发症,因此ERCP术中要注意保护Oddi括约肌.Oddi括约肌是十二指肠乳头(DP)的主要结构之一,内镜医师在注意保护Oddi括约肌的同时,常常忽略了对DP其他结构的保护,如EST及EPLBD对缠头皱襞的损伤、针状刀开窗对DP黏膜的损伤等.此外,DP本身可能存在多种疾病,例如十二指肠乳头炎、十二指肠乳头旁憩室、胆胰合流异常等.DP疾病不仅会影响胆汁及胰液的排泄,还会继发胆胰系统炎症、结石和肿瘤.本文对DP的结构及功能、EST和EPBD对DP的损伤、ERCP中如何保护DP三个维度进行阐述,希望ERCP在发挥治疗胆道、胰管和DP疾病的同时减少对正常DP的损伤,促进ERCP技术的健康发展.
Endoscopic retrograde cholangiopancreatography(ERCP)is one of the preferred options for treating common bile duct stones,bile duct stenosis,and bile leakage.Endoscopic sphincterotomy(EST)and endoscopic papillary balloon dilation(EPBD)can reduce the difficulty of stone removal and increase the stone clearance rate.However,EST and endoscopic papillary large balloon dilation(EPLBD)can also damage the Oddi sphincter and even cause long-term complications such as reflux cholangitis and stone recurrence.Therefore,it is necessary to protect the Oddi sphincter during ERCP.The Oddi sphincter is one of the main structures of duodenal papilla(DP).While endoscopists pay attention to protecting the Oddi sphincter,they often neglect the protection of other structures of the DP,such as the damage to the papillary folds caused by EST and EPLBD,and the damage to the DP mucosa caused by needle-knife.In addition,the DP has various diseases,such as duodenal papillitis,periampullary diverticula,and pancreaticobiliary maljunction.DP diseases not only affect the excretion of bile and pancreatic juice but also can lead to secondary inflammation,stones,and tumors in the biliary and pancreatic systems.This article will elaborate on three aspects:the structure and function of the DP,the damage to the DP caused by EST and EPBD,and how to protect the DP during ERCP.It is hoped that ERCP can leverage its advantages in treating biliary tract,pancreatic duct and DP diseases while minimizing damage to normal DP.
张诚;杨玉龙
同济大学附属东方医院胆石病中心,上海 200120同济大学附属东方医院胆石病中心,上海 200120
医药卫生
内镜逆行胰胆管造影十二指肠乳头十二指肠皱襞内镜下乳头括约肌切开内镜下乳头球囊扩张Oddi括约肌
endoscopic retrograde cholangiopancreatographyduodenal papilladuodenal foldendoscopic sphincterotomyendoscopic papillary balloon dilationsphincter of Oddi
《肝胆胰外科杂志》 2026 (6)
381-388,8
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