早期龋管理研究进展OA
Research progress in early caries management
局限于牙釉质的早期龋是实现龋病非手术干预的关键窗口.目前,龋病管理已从传统的"钻-补"模式转向以龋风险管理和龋损管理为核心的现代模式.本文基于龋病管理的最新理念,系统性综述了早期龋管理各方面的研究进展,包括龋风险评估、早期诊断、治疗方案选择及随访监测,总结了当前面临的主要挑战,并就人工智能在早期龋管理中的运用进行了总结和展望.在龋风险管理方面,美国牙科协会系统、龋病风险评估管理系统、Cariogram系统和龋风险评估工具等仍是临床主流工具,但人工智能技术的引入提供了更高维度、更多因素整合的预测能力,有望提升风险分层的准确性.在早期诊断方面,视诊、探诊与咬翼片仍是基础手段,但对早期龋尤其是邻面病变的灵敏度有限;定量光诱导荧光、光学相干断层扫描、近红外光透照、光纤透照、激光荧光等光学技术的应用使龋损特征数字化,为脱矿程度分析、活跃性判断及人工智能模型构建提供了数据基础.早期龋的治疗以无创和微创方式为主,再矿化治疗适用于浅表病损,渗透树脂兼具阻断进展及改善美观的优势,微研磨和漂白可作为美学处理的补充手段;激光、臭氧及光动力等新技术亦展现出潜在应用价值.治疗方案制定需综合龋活跃性、患者龋风险状态、脱矿深度、依从性与治疗意愿等因素,但目前脱矿深度仍难以精准定量,决策依据缺乏标准化.在随访管理方面,需基于风险分层制定个体化复查间隔,关注病损变化、患者依从性及复发风险.综上所述,智能化与精准化将成为未来早期龋管理的发展方向,AI在风险预测、图像分析和临床决策支持等方面的应用有望进一步提升早期龋的诊疗效率与效果.
Early caries confined to the enamel layer represent a critical window for achieving noninvasive interven-tion in caries management.Caries management has shifted from the traditional"drill-and-fill"model toward a modern paradigm centered on caries risk and lesion management.Based on contemporary concepts,this review systematically summarizes recent advances in early caries management,including caries risk assessment,early diagnosis,treatment strategy selection,and follow-up monitoring,while highlighting the major challenges currently being faced,and further reviewing and discussing the application of artificial intelligence(AI)in early caries management.In terms of risk man-agement,conventional systems including the American Dental Association,Caries Management by Risk Assessment,Cariogram,and the Caries-Risk Assessment Tool remain mainstays in clinical practice.However,AI offers predictive capability through higher-dimensional data processing and the integration of numerous influencing factors,with the po-tential to improve the accuracy of risk stratification.For diagnosis,visual inspection,tactile examination,and bitewing radiography remain fundamental methods,yet their sensitivity for early caries—particularly proximal lesions—is lim-ited.The application of optical technologies,including quantitative light-induced fluorescence,optical coherence tomog-raphy,near-infrared light transillumination,fiber-optic transillumination,and laser-induced fluorescence,enables digi-tal characterization of caries lesions,providing a data foundation for demineralization assessment,lesion activity evalua-tion,and AI model development.The management of early caries primarily relies on noninvasive and minimally inva-sive approaches.Remineralization therapy is suitable for superficial lesions,resin infiltration offers the dual advantages of inhibiting lesion progression and improving aesthetics,and microabrasion and bleaching may serve as adjunctive aes-thetic treatments.Emerging modalities such as laser,ozone,and photodynamic therapy have also demonstrated poten-tial.Treatment decision-making should comprehensively consider lesion activity,patient caries risk status,demineraliza-tion depth,patient compliance,and treatment preferences.However,precise quantification of demineralization depth re-mains challenging,and standardized decision-making criteria are still lacking.Follow-up management should be indi-vidualized based on risk stratification,with attention to lesion changes,patient compliance,and the risk of recurrence.In summary,intelligent and precision-based approaches are expected to define the future of early caries management,and the application of AI in risk prediction,image analysis,and clinical decision support is anticipated to further en-hance the efficiency and effectiveness of early caries diagnosis and treatment.
赵梅;梁羽童;何金枝;程磊
口腔疾病防治全国重点实验室 国家口腔医学中心 口腔疾病国家临床医学研究中心 四川大学华西口腔医院牙体牙髓病科,四川 成都(610041)口腔疾病防治全国重点实验室 国家口腔医学中心 口腔疾病国家临床医学研究中心 四川大学华西口腔医院牙体牙髓病科,四川 成都(610041)口腔疾病防治全国重点实验室 国家口腔医学中心 口腔疾病国家临床医学研究中心 四川大学华西口腔医院牙体牙髓病科,四川 成都(610041)口腔疾病防治全国重点实验室 国家口腔医学中心 口腔疾病国家临床医学研究中心 四川大学华西口腔医院牙体牙髓病科,四川 成都(610041)
医药卫生
早期龋龋病管理龋风险评估早期诊断再矿化治疗微创治疗人工智能
early cariescaries managementcaries risk assessmentearly diagnosisremineralization therapyminimally invasive treatmentartificial intelligence
《口腔疾病防治》 2026 (6)
585-594,10
国家自然科学基金(82271033)四川省卫生健康委员会(23LCYJ016)四川大学华西口腔医院临床研究项目(LCYJ-QN-202515) This study was supported by the grants from the National Natural Science Foundation of China(No.82271033),Sichuan Provincial Health Commission(No.23LCYJ016),Clinical Research Program of West China Hospital of Stomatology,Si-chuan University(No.LCYJ-QN-202515).
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