中老年午睡频率、时长与心绞痛相关性分析OA

Objective:To explore the association between the duration and frequency of napping and the incidence of angina pectoris(AP).Methods:A total of 2,269 subjects from the Sleep Heart Health Study were selected.Baseline data and napping habits(duration and frequency)were collected.The first diagnosed cases of angina pectoris during an average follow-up period of 11 years were recorded.Logistic regression analysis was used to evaluate the correlation between napping duration and fre-quency and the incidence of angina pectoris.Results:Significant differences were observed among groups with different napping frequencies(0 times/week,1～2 times/week,3～4 times/week,and≥5 times/week)and durations(0 minutes,<30 minutes,and≥30 minutes)in terms of gender,age,body mass index(BMI),alcohol consumption,blood lipid levels(total cholesterol,high-density lipoprotein,triglycerides),diabetes,hypertension,and angina pectoris(P<0.05).After adjusting for confounding factors,the study found that napping habits of≥5 times/week(OR=1.65,95%CI=1.27～2.14,P<0.001)and≥30minutes(OR=1.92,95%CI=1.41～2.61,P<0.001)were independently associated with an increased prevalence of angi-na pectoris.It was found in different subgroups that the association between napping frequency and angina pectoris was more significant in the population aged<60 years(Pinteraction=0.009),while no significant interaction effect was observed in other subgroup analyses.Conclusion:A napping frequency of≥5 times per week and a daily napping duration of≥30 minutes can significantly increase the risk of angina pectoris.Improving napping habits may have positive significance for reducing the occurrence of angina pectoris.