火龙罐综合灸治疗寒湿痹阻型膝骨关节炎的临床疗效观察OA
Clinical Observation on the Efficacy of Fire Dragon Cupping Comprehensive Moxibustion in the Treatment of Knee Osteoarthritis with Cold-Dampness Obstruction Syndrome
目的:探讨火龙罐综合灸干预寒湿痹阻型膝骨关节炎(Knee Osteoarthritis,KOA)的临床疗效及安全性.方法:将120例寒湿痹阻型膝骨关节炎患者随机分为对照组、干预Ⅰ组和干预Ⅱ组各40例,对照组给予口服依托考昔片治疗,干预Ⅰ组在对照组的基础上给予中药封包治疗,干预Ⅱ组在对照组的基础上给予火龙罐综合灸治疗,比较三组患者治疗前后西安大略和麦克马斯特大学骨关节炎指数(Western Ontario and McMaster Universities,WOMAC)评分、膝关节活动度(Range of Motion,ROM)、疼痛视觉模拟评分(Visual Analogue Pain Score,VAS)评分及血清白细胞介素-6(Interleukin-6,IL-6)、C反应蛋白(C-Reactive Protein,CRP)、血沉(Erythrocyte Sedimentation Rate,ESR)水平.结果:与治疗前相比,三组患者治疗后VAS评分、WOMAC评分显著降低(P<0.01),ROM显著升高(P<0.01),IL-6、CRP、ESR显著降低(P<0.05).与对照组相比,干预Ⅰ组、干预Ⅱ组治疗后VAS评分、WOMAC评分显著降低(P<0.01),ROM显著升高(P<0.01),IL-6、CRP、ESR差异无统计学意义(P>0.05);与干预Ⅰ组相比较,干预Ⅱ组治疗后VAS评分、ROM差异有统计学意义(P<0.05),IL-6、CRP、ESR差异无统计学意义(P>0.05).与对照组相比,干预Ⅱ组临床疗效显著升高(P<0.01),干预Ⅰ组临床疗效有显著性差异(P<0.05).此外,三组患者在研究期间均未出现不良反应.结论:火龙罐综合灸可有效缓解寒湿痹阻型膝骨关节炎患者的疼痛,改善关节功能,减轻炎症反应,提高关节活动度,值得临床推广使用.
Objective:To investigate the clinical efficacy and safety of Fire Dragon Cupping Comprehensive Moxibustion in the treatment of knee osteoarthritis(KOA)with cold-dampness obstruction syndrome.Methods:A total of 120 patients with KOA of the cold-dampness obstruction syndrome were randomly divided into a control group,intervention group Ⅰ,and intervention group Ⅱ,with 40 cases in each group.The control group received oral etoricoxib tablets.Intervention group Ⅰ received Chinese herbal medicine compress therapy in addition to the treatment administered to the control group.Intervention group Ⅱ received Fire Dragon Cupping Comprehensive Moxibustion in addition to the treatment administered to the control group.The Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC)scores,knee range of motion(ROM),visual analogue scale(VAS)pain scores,and serum levels of Interleukin-6(IL-6),C-reactive protein(CRP),and erythrocyte sedimentation rate(ESR)were compared among the three groups before and after treatment.Results:Compared with pre-treatment values,VAS scores and WOMAC scores were significantly decreased(P<0.01),ROM was significantly increased(P<0.01),and IL-6,CRP,and ESR levels were significantly decreased(P<0.05)in all three groups after treatment.Compared with the control group,both intervention group Ⅰ and intervention group Ⅱ showed significantly lower VAS scores and WOMAC scores(P<0.01)and significantly higher ROM(P<0.01)after treatment,while no statistically significant differences were observed in IL-6,CRP,or ESR levels(P>0.05).Compared with intervention group Ⅰ,intervention group Ⅱ showed statistically significant differences in VAS scores and ROM(P<0.05),whereas no statistically significant differences were found in IL-6,CRP,or ESR levels(P>0.05).Compared with the control group,the clinical efficacy of intervention group Ⅱ was significantly higher(P<0.01),and that of the intervention group Ⅰ showed a statistically significant difference(P<0.05).In addition,no adverse reactions were reported in any of the three groups during the study period.Conclusion:Fire Dragon Cupping Comprehensive Moxibustion can effectively alleviate pain,improve joint function,reduce inflammatory response,and enhance joint mobility in patients with KOA of the cold-dampness obstruction pattern,and is worthy of clinical promotion and application.
高峰;寸淑娟;万青;韦佳佳;陈思瑾;陈涛
云南中医药大学第一附属医院,云南 昆明 650021云南中医药大学,云南 昆明 650500云南中医药大学第一附属医院,云南 昆明 650021||云南中医药大学,云南 昆明 650500云南中医药大学第一附属医院,云南 昆明 650021云南贞和中医馆,云南 昆明 650051云南中医药大学第一附属医院,云南 昆明 650021
医药卫生
膝骨关节炎寒湿痹阻火龙罐综合灸中药封包疼痛炎症因子
knee osteoarthritiscold-dampness obstruction patternfire dragon cupping comprehensive moxibustionChinese herbal medicine compresspaininflammatory factors
《中医康复》 2026 (6)
31-37,7
云南中医药大学护理专项基金(YZHY202317)云南中医药大学校院联合基金(XYLH2023121)云南省科技厅基础研究计划中医联合专项(202301AZ070001-145)云南省科技厅基础研究计划中医联合专项(202401AZ070001-053)
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