基于rs-fMRI低频振幅比率分析推拿治疗腰椎间盘突出症的高级中枢机制研究OA

Objective:To study the potential central mechanism of Tuina in the treatment of lumbar disc herniation based on resting-state functional magnetic resonance imaging(rs-fMRI).Methods:A total of 72 patients with lumbar disc herniation were randomly divided into the control group(36 cases)and the treatment group(36 cases,1 case dropped out).The control group was treated with transcutaneous electrical nerve stimulation combined with traction,while the treatment group was treated with Tuina,once a day.Both groups were treated for 14 times.The visual analogue scale(VAS score)and self-rating depression scale(SDS score)were compared between the two groups before and after treatment.After treatment,rs-fMRI data were collected to observe the changes of low frequency amplitude ratio(fALFF)in the two groups.Results:Before treatment,there was no significant difference in VAS and SDS scores between the two groups(P>0.05).After treatment,the VAS score and SDS score of the two groups were significantly lower than those before treatment,and the difference was statistically significant(P<0.05).There was no significant difference in VAS score between the treatment group and the control group(P>0.05),but the SDS score was significantly lower than that of the control group(P<0.05).After treatment,the fALFF value of the treatment group was lower than that of the control group in the left angular gyrus(Angular.L),and the left inferior frontal gyrus triangle(IFGtri.L)was increased,and the difference was statistically significant(P<0.05).Conclusion:Tuina may relieve pain and improve depression by regulating the local brain function of the left angular gyrus and left triangular part of inferior frontal gyrus in patients with lumbar disc herniation.