类器官技术在中医药领域应用前景的系统回顾与展望OA

As a major technological breakthrough,human 3D organoid technology,through revealing the growth status,struc-ture,function and characteristics of tissue or organs,bridges the long-standing gap between developmental biology and precision medicine.It plays an important role in reconstructing in vitro experimental models capable of truly simulating the human liver.At present,organoid technology is in a period of rapid development,and its structure and functional simulation of their organizations and organs are gradually increasing.With the increasing level of summarizing the internal organ structure and artificial tissue or-gans in organoid systems,its application fields are also becoming more and more extensive.The combination of organoid systems and chip technology has opened up a new field of organoid engineering,which is expected to solve the challenges faced by exist-ing organoid systems and expand their biomedical applications.At the same time,in terms of the quality control,efficacy evalua-tion and composite compatibility in traditional Chinese medicine,the technology will also play an extremely important role.