首页|期刊导航|中国合理用药探索|某口腔专科医院门诊口腔黏膜病的用药情况分析

某口腔专科医院门诊口腔黏膜病的用药情况分析OA

Analysis of Medication Use in Outpatients with Oral Mucosal Diseases in a Specialized Stomatology Hospital

中文摘要英文摘要

目的:了解某口腔专科医院门诊口腔黏膜病各种诊断处方数量分布及临床用药情况.方法:选取 2022 年 6~8月该院口腔黏膜病患者的电子处方进行回顾性分析,分析不同口腔黏膜病诊断的分布及各类药物使用情况,并对处方数排名前5位的疾病进行具体分析.结果:该院口腔黏膜病涉及36种临床诊断,其中处方数量排名前 5 位的临床诊断依次为口腔扁平苔藓(OLP)、复发性阿弗他溃疡(RAU)、口炎、舌炎和唇炎.处方涉及口服药 32 种(4531张)、外用药19 种(3800 张)、注射液 9 种(1925 张),药物治疗以全身用药、局部用药和局部封闭治疗为主.在排名前 5 位的疾病用药中,存在部分超说明书用药情况.结论:该院口腔黏膜病临床诊断广,但药品种类有限,药物治疗方案中存在超说明书用药情况.针对该院药品有限的现状,未来可考虑加强超说明书用药管理,开展临床研究拓宽药物适应症,开发药品新剂型及研制新的医院制剂,为临床诊治口腔黏膜病提供更多选择.

Objective:To investigate the distribution of diagnoses and clinical medication use in outpatients with oral mucosal diseases in a specialized stomatology hospital.Methods:Electronic prescriptions of patients with oral mucosal diseases from June to August 2022 were retrospectively analyzed.The distribution of different oral mucosal disease diagnoses and the use of various drugs were analyzed,with specific analysis on the top 5 diseases by prescription number.Results:A total of 36 clinical diagnoses of oral mucosal diseases were included,among which the top 5 diseases by prescription number were oral lichen planus(OLP),recurrent aphthous ulcer(RAU),stomatitis,glossitis and cheilitis.A total of 32 oral drugs(4531 prescriptions),19 topical drugs(3800 prescriptions)and 9 injections(1925 prescriptions)were involved.Drug therapy was dominated by systemic administration,topical administration and local blocking therapy.Partial off-label drug use was found in the top 5 diseases.Conclusion:The hospital covers a wide range of oral mucosal diseases,but the types of drugs are limited.Partial off-label drug use cases are found in drug treatment regimens.In view of the limited drugs in the hospital,future efforts can be made to strengthen the management of off-label drug use,carry out clinical research to expand drug indications,develop new dosage forms and new hospital preparations,so as to provide more options for clinical diagnosis and treatment of oral mucosal diseases.

夏骏杰;王晨;应杰;陈钦;魏子豪

浙江大学医学院附属邵逸夫医院药学部,杭州 310016浙江大学医学院附属邵逸夫医院药学部,杭州 310016浙江大学医学院附属邵逸夫医院药学部,杭州 310016浙江大学医学院附属邵逸夫医院药学部,杭州 310016浙江大学医学院附属口腔医院·浙江大学口腔医学院·浙江省口腔疾病临床医学研究中心,杭州 310009

医药卫生

回顾性分析口腔专科医院口腔黏膜病用药分析医院制剂

retrospective analysisspecialized stomatology hospitaloral mucosal diseasesdrug use analysishospital preparations

《中国合理用药探索》 2026 (4)

1-7,7

国家自然科学基金(82401099)

10.3969/j.issn.2096-3327.2026.04.001

评论