首页|期刊导航|中国医学创新|通窍化瘀利水汤联合脑室-腹腔分流术治疗特发性正常压力脑积水的效果

通窍化瘀利水汤联合脑室-腹腔分流术治疗特发性正常压力脑积水的效果OA

Effect of Tongqiao Huayu Lishui Decoction Combined with Ventriculoperitoneal Shunt in the Treatment of Idiopathic Normal Pressure Hydrocephalus

中文摘要英文摘要

目的:探讨脑室-腹腔分流术治疗特发性正常压力脑积水的基础上加用通窍化瘀利水汤的效果.方法:选取 2023 年 9 月—2025 年 3 月湖南省中医药大学第二附属医院收治的 102 例特发性正常压力脑积水患者,采用随机数字表法将其分为观察组和对照组,每组 51 例.对照组采取脑室-腹腔分流术治疗,观察组在对照组基础上联合通窍化瘀利水汤治疗.术后 4 周评估并比较两组临床疗效.比较两组术前、术后 4 周中医证候积分、神经功能、生活质量.结果:术后 4 周,观察组 NIHSS 评分、中医证候积分低于对照组(P<0.05);术后 4 周,观察组 Tinetti 步态评估量表评分、生活质量综合评定问卷-74各维度评分高于对照组(P<0.05).术后 4 周,观察组治疗总有效率高于对照组(P<0.05).结论:对行脑室-腹腔分流术治疗的特发性正常压力脑积水患者联合通窍化瘀利水汤治疗能够改善患者的神经功能损伤情况,改善中医证候积分,有效提高临床疗效.

Objective:To explore the effect of adding Tongqiao Huayu Lishui Decoction on the basis of ventriculoperitoneal shunt in the treatment of idiopathic normal pressure hydrocephalus.Method:A total of 102 patients with idiopathic normal pressure hydrocephalus admitted to the Second Affiliated Hospital of Hunan University of Chinese Medicine from September 2023 to March 2025 were selected.They were divided into the observation group and the control group by the random number table method,with 51 cases in each group.The control group was treated with ventriculoperitoneal shunt,while the observation group was treated with Tongqiao Huayu Lishui Decoction on the basis of the control group.The clinical efficacy of the two groups was evaluated and compared at 4 weeks after the operation.The TCM syndrome scores,neurological functions and quality of life of the two groups before the operation and 4 weeks after the operation were compared.Result:Four weeks after the operation,the NIHSS scores and TCM syndrome scores in the observation group were lower than those in the control group(P<0.05).Four weeks after operation,the Tinetti gait assessment scale score and all dimensions of the generic quality of life inventory-74 scores in the observation group were higher than those in the control group(P<0.05).Four weeks after operation,the total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).Conclusion:For patients with idiopathic normal pressure hydrocephalus undergoing ventriculoperitoneal shunt,combined treatment with Tongqiao Huayu Lishui Decoction can improve the neurological function impairment of the patients,enhance the TCM syndrome score,and effectively improve the clinical efficacy.

王余燕;刘亮

湖南省中医药大学第二附属医院神经外科 湖南 长沙 410005宁乡市人民医院神经外科 湖南 宁乡 410600

通窍化瘀利水汤脑室-腹腔分流术特发性正常压力脑积水

Tongqiao Huayu Lishui DecoctionVentriculoperitoneal shuntIdiopathic normal pressure hydrocephalus

《中国医学创新》 2026 (12)

28-32,5

10.3969/j.issn.1674-4985.2026.12.007

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