中西医结合内外兼治法治疗痰热闭肺型小儿肺炎支原体肺炎的效果OA
Effect of Integrated Traditional Chinese and Western Medicine with Internal and External Treatment on Mycoplasma Pneumoniae Pneumonia in Children with Phlegm-heat Blocking the Lungs Type
目的:探讨痰热闭肺型小儿肺炎支原体肺炎采用中西医结合内外兼治法治疗的效果及安全性.方法:选取瑞金市中医院 2022 年 6 月—2024 年 6 月收治的痰热闭肺型肺炎支原体肺炎患儿 108 例作为研究对象,采用随机数字表法分为对照组和试验组,各 54 例.两组均接受常规治疗,对照组给予盐酸氨溴索雾化吸入治疗,试验组在对照组基础上给予麻杏石甘汤加减联合中药穴位敷贴治疗.比较两组症状评分、炎症指标[血清淀粉样蛋白 A(SAA)、TNF-α]、肺功能指标[每分钟通气量(VE)、潮气量(TV)]、心肌酶指标[肌酸激酶(CK)、乳酸脱氢酶(LDH)]变化情况,并对比两组治疗总有效率及不良反应发生率.结果:治疗 1 周后,试验组症状总评分低于对照组(P<0.05).治疗 1 周后,试验组治疗总有效率高于对照组(P<0.05).治疗 1 周后,试验组 SAA、TNF-α、CK、LDH 水平低于对照组,VE、TV 水平均高于对照组(P<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论:痰热闭肺型肺炎支原体肺炎患儿在雾化吸入盐酸氨溴索基础上,予以麻杏石甘汤加减及中药穴位敷贴治疗,可减轻炎症反应,促进不适症状减退及肺功能恢复,抑制肺炎对心肌的损害,且安全性较好.
Objective:To explore the efficacy and safety of integrated traditional Chinese and western medicine with internal and external treatment method on Mycoplasma pneumoniae pneumonia in children with phlegm-heat blocking the lungs type.Method:A total of 108 children with Mycoplasma pneumoniae pneumonia with phlegm-heat blocking the lungs type admitted to Ruijin Traditional Chinese Medicine Hospital from June 2022 to June 2024 were selected as the research objects.They were divided into the control group and the experimental group by random number table method,with 54 cases in each group.Both groups received conventional treatment.The control group was given Ambroxol Hydrochloride nebulized inhalation therapy,while the experimental group was treated with modified Ma Xing Shi Gan Decoction combined with traditional Chinese medicine acupoint application on the basis of the control group.The changes in symptom scores,inflammatory indicators[serum amyloid A(SAA),TNF-α],pulmonary function indicators[ventilation per minute(VE),tidal volume(TV)],and myocardial enzyme indicators[creatine kinase(CK),lactate dehydrogenase(LDH)]were compared between the two groups,and the total effective rate of treatment and the incidence of adverse reactions were also compared between the two groups.Result:One week after the treatment,the total symptom score of the experimental group was lower than that of the control group(P<0.05).One week after the treatment,the total effective rate of the experimental group was higher than that of the control group(P<0.05).One week after the treatment,the levels of SAA,TNF-α,CK and LDH in the experimental group were lower than those in the control group,while the levels of VE and TV were higher than those in the control group(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:For children with Mycoplasma pneumoniae pneumonia of the phlegm-heat blocking the lungs type,on the basis of nebulized inhalation of Ambroxol Hydrochloride,treatment with modified Ma Xing Shi Gan Decoction and traditional Chinese medicine acupoint application can reduce inflammatory responses,promote the reduction of uncomfortable symptoms and the recovery of lung function,inhibit the damage of pneumonia to the myocardium,and demonstrate good safety.
刘芳芳;钟海岩;钟龙珠
瑞金市中医院儿科 江西 瑞金 342500瑞金市中医院儿科 江西 瑞金 342500瑞金市中医院儿科 江西 瑞金 342500
小儿肺炎支原体肺炎痰热闭肺型麻杏石甘汤加减中药穴位敷贴盐酸氨溴索雾化吸入
Mycoplasma pneumoniae pneumonia in childrenPhlegm-heat blocking the lungs typeModified Ma Xing Shi Gan DecoctionTraditional Chinese medicine acupoint applicationAmbroxol HydrochlorideNebulization inhalation
《中国医学创新》 2026 (10)
15-20,6
评论