首页|期刊导航|中国医学创新|益肾补骨汤对骨质疏松性胸腰椎骨折PVP术后患者骨密度及腰椎功能的影响

益肾补骨汤对骨质疏松性胸腰椎骨折PVP术后患者骨密度及腰椎功能的影响OA

Effect of Yishen Bugu Decoction on Bone Density and Lumbar Spine Function in Patients with Osteoporotic Thoracolumbar Fractures after PVP

中文摘要英文摘要

目的:探究益肾补骨汤对骨质疏松性胸腰椎骨折经皮椎体成形术(PVP)术后患者骨密度及腰椎功能的影响.方法:按随机数字表法将 2024 年 9 月—2025 年 7 月贵州中医药大学第一附属医院收治的 86 例骨质疏松性胸腰椎骨折 PVP 术后患者分为对照组与观察组,各 43 例,对照组采用抗骨质疏松药物碳酸钙 D3 治疗,观察组在对照组基础上加用益肾补骨汤,比较两组骨密度、腰椎功能、疼痛程度及不良反应.结果:治疗 6 周后,观察组腰椎正位、右侧股骨颈骨密度较对照组高(P<0.05),治疗 3、6 周后,观察组ODI、VAS评分较对照组低,JOA评分较对照组高(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05).结论:益肾补骨汤可提升骨质疏松性胸腰椎骨折PVP术后患者骨密度,改善腰椎功能,减轻术后疼痛,安全性较好.

Objective:To investigate the effects of Yishen Bugu Decoction on bone density and lumbar spine function in patients with osteoporotic thoracolumbar fractures after percutaneousvertebro plasty(PVP).Method:A total of 86 patients with osteoporotic thoracolumbar fractures after PVP admitted to the First Affiliated Hospital,Guizhou University of Traditional Chinese Medicine from September 2024 to July 2025 were randomly divided into the control group and the observation group using a random number table method,with 43 cases in each group.The control group received calcium carbonate D3 as anti-osteoporosis medication,while the observation group received Yishen Bugu Decoction in addition to the control treatment.Comparison was made on bone density,lumbar spine function,pain severity,and adverse reactions between the two groups.Result:After 6 weeks of treatment,the observation group showed higher bone density in anteroposterior view of the lumbar spine and right femoral neck compared to the control group(P<0.05).After 3 weeks and 6 weeks post-treatment,the observation group exhibited lower ODI and VAS scores and higher JOA scores compared to the control group(P<0.05).No significant difference in the incidence of adverse reactions was observed between the groups(P>0.05).Conclusion:Yishen Bugu Decoction can improve bone density,enhance lumbar spine function,reduce postoperative pain,and demonstrate good safety in patients with osteoporotic thoracolumbar fractures after PVP.

夏兴隆;胡广;李雪琪

贵州中医药大学 贵州 贵阳 550002贵州中医药大学第一附属医院脊柱外科 贵州 贵阳 550001贵州中医药大学 贵州 贵阳 550002

骨质疏松性胸腰椎骨折经皮椎体成形术益肾补骨汤骨密度腰椎功能

Osteoporotic thoracolumbar fracturePercutaneousvertebro plastyYishen Bugu DecoctionBone densityLumbar spine function

《中国医学创新》 2026 (10)

6-10,5

10.3969/j.issn.1674-4985.2026.10.002

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