北京成人认知功能减退现况及相关因素OACHSSCD

Objective:To describe the prevalence of cognitive decline among adult residents in Beijing,and to examine the associations between sociodemographic and physical health factors,and common mental disorders with cognitive decline.Methods:A cross-sectional survey was conducted using a stratified,four-stage,unequal-probabili-ty complex sampling design to randomly select permanent residents aged≥18 years from Beijing.Licensed psychi-atrists conducted cognitive screening and assessments and diagnoses of common mental disorders based on the Structured Clinical Interview for DSM-5 Disorders,Research Version(SCID-5-RV).The prevalence of subjective cognitive decline(SCD)and cognitive decline were estimated.Logistic regression analyses were conducted to iden-tify associations with sociodemographic characteristics and physical diseases,while Rao-Scott χ2 tests were applied to examine the associations between common mental disorders and cognitive outcomes.Results:A total of 10 778 a-dults completed the survey.The prevalences of SCD and cognitive decline among adults were 9.6%and 2.9%,re-spectively.Logistic regression analyses indicated that SCD was associated with female sex(OR=1.3),urban resi-dence(OR=1.5),and chronic physical diseases(OR=2.2).Cognitive decline was associated with older age(≥70 years:OR=4.8;60-69 years:OR=3.6),lower educational attainment(primary school or below:OR=8.4;junior high school:OR=4.3;vocational/high school:OR=2.4),rural residence(OR=1.8),and chronic physical diseases(OR=3.2).The prevalence of SCD and cognitive decline among individuals with common mental disor-ders(24.5%and 5.6%,respectively)were significantly higher than those among individuals without mental disor-ders.Conclusion:The prevalences of SCD and cognitive decline among adults are associated with factors including age,sex,educational attainment,residential area,and chronic physical diseases.Mental disorders-particularly depres-sive disorders-are significantly associated with cognitive decline.