经典名方大补元煎的关键信息考证OA

Dabuyuanjian is one of the classic famous formulas in the Catalog of Ancient Classic Famous Formulas(Second Batch)-Medicine of Han Ethnic Group.It consists of Ginseng Radix et Rhizoma,Dioscoreae Rhizoma,Rehmanniae Radix Praeparata,Eucommiae Cortex,Angelicae Sinensis Radix,Corni Fructus,Lycii Fructus,and Glycyrrhizae Radix et Rhizoma Praeparata cum Melle,and is used to treat the symptoms of men and women who have a great loss of Qi and blood and a critical and dramatic loss of spiritual guardianship.This study reviewed the ancient and modern literature,and used literature tracing and bibliometrics methods to mine the key information of the historical origin,formula name,drug composition,compatibility,drug dosage,original plants and processing of drugs,decocting method,and clinical application of Dabuyuanjian.The results showed that Dabuyuanjian was first recorded in the Jing Yue's Collected Works(Jing Yue Quan Shu),with the dosage mainly following the original formula.According to the dosage in the Ming and Qing dynasties,the formula is composed of 5.60 g(for mild cases)/39.17 g(for severe cases)Ginseng Radix et Rhizoma,7.46 g Dioscoreae Rhizoma,9.32 g(for mild cases)/93.25 g(for severe cases)Rehmanniae Radix Praeparata,7.46 g Eucommiae Cortex,9.32 g Angelicae Sinensis Radix,3.73 g Corni Fructus,9.32 g Lycii Fructus,and 5.60 g Glycyrrhizae Radix et Rhizoma Praeparata cum Melle.Regarding the original plants of drugs,Ginseng Radix et Rhizoma is produced from the dried roots and rhizomes of Panax ginseng,Dioscoreae Rhizoma from stir-fried dried rhizomes of Dioscorea opposita,Rehmanniae Radix Praeparata from steamed dried roots of Rehmannia glutinosa,Eucommiae Cortex from the dried bark of Eucommia ulmoides,Angelicae Sinensis Radix from the dried roots of Angelica sinensis,Corni Fructus from the dried mature fruit flesh of Cornus officinalis,Lycii Fructus from the dried mature fruits of Lycium barbarum,and Glycyrrhizae Radix et Rhizoma Praeparata cum Melle from the honey-processed dried roots and rhizomes of Glycyrrhiza uralensis.These medicinal materials are decocted in 400 mL water to reach a volume of 140 mL,and the decoction should be taken 1 h after meals,2-3 doses per day.Dabuyuanjian has a wide range of clinical applications,including gynecological and obstetrical diseases,deficiency,baffling and panic,consumptive thirst,and blood,ear,nose,and throat diseases.In modern clinical practice,it is mainly used for diseases of the nervous system,gynecology,urinary system,cardiovascular system,digestive system,musculoskeletal system,connective tissue,immune system,blood,and men.Through the review of ancient and modern literature,this study sorted out the historical evolution and mined the key information of Dabuyuanjian,aiming to provide a theoretical reference for safe and effective clinical application and subsequent research and development of this formula.