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基于深度神经网络的糖尿病发病风险评估OA

Diabetes Mellitus Onset Risk Assessment Based on Deep Neural Networks

中文摘要英文摘要

本研究构建了一个基于深度神经网络的糖尿病发病风险评估模型.实验数据来源于NAGALA(1994-2016)队列,共纳入人口学信息、生化指标等 19 个特征.采取基于聚类的自适应采样方法解决类不均衡问题.随后构建三层深度神经网络模型,利用SHAP分析法划分高、低风险组.最后通过对比分析和风险评估效果分析,验证模型性能.结果表明,HbA1c、FPG、年龄和BMI为糖尿病发生的主要影响因素.深度神经网络模型在各随访周期中均能有效区分是否患病,性能优于其他机器学习模型.高、低风险组在整体及具体指标上均存在显著差异.该糖尿病发病风险评估模型能够准确预测糖尿病发病情况及其发病风险,为糖尿病早期筛查和风险评估提供了有力工具.

This study constructed a diabetes mellitus risk assessment model based on deep neural network.The experimental data were from the NAGALA(1994-2016)cohort,including 19 characteristics such as demographic information and biochemical indicators.An adaptive sampling method based on clustering is adopted to solve the problem of class imbalance.Then,a three-layer deep neural network model is constructed,and the SHAP analysis method is used to divide the high and low risk groups.Finally,the performance of the model is verified by comparative analysis and risk assessment effect analysis.The results showed that HbA1c,FPG,age and BMI were the main influencing factors of diabetes mellitus.The deep neural network model can effectively distinguish whether the patient is sick in each follow-up period,and its performance is better than other machine learning models.There are significant differences in the overall and specific indicators between the high and low risk groups.The diabetes mellitus risk assessment model can accurately predict the incidence and risk of diabetes mellitus,and provides a powerful tool for early screening and risk assessment of diabetes mellitus.

李梓露;宋浩;刘艳枚

昆明理工大学信息工程与自动化学院,云南 昆明 650000新疆工业学院新能源与矿业学院,新疆 和田 840000广州医科大学附属清远医院第六临床学院,广州 清远 511500

医药卫生

糖尿病深度神经网络风险评估

Diabetes mellitusDeep neural networksRisk assessment

《医学信息》 2026 (9)

66-71,6

10.3969/j.issn.1006-1959.2026.09.010

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