基于"脾肾同治"探讨山药在糖尿病肾病防治中的作用OA
Role of Shanyao(Dioscoreae Rhizoma)in preventing and treating diabetic kidney disease based on"simultaneous treatment of the spleen and kidney"
本文从中医理论出发,阐释了脾肾生理关联、糖尿病肾病中脾肾两虚的病机演变及"脾肾同治"的分期应用策略,并基于"脾肾同治"理论系统梳理山药在糖尿病肾病防治中的作用,通过查阅相关中医经典古籍,考证了诸多纳入山药的防治糖尿病肾病的经典方剂,并对其配伍组方、剂量、炮制方法、服用方法、功效主治等进行了梳理分析.通过系统梳理发现山药高度契合DKD脾肾两虚的病机,是"脾肾同治"理论指导下防治糖尿病肾病的理想用药.本文为临床精准运用山药防治糖尿病肾病及优化糖尿病肾病中医防治方案提供了理论依据,也为后续深入开展山药防治DKD的现代药理与临床研究奠定了基础.
Starting from TCM theory,this paper elucidates the physiological relationship between the spleen and kidney,the pathogenesis evolution of spleen-kidney deficiency in diabetic kidney disease(DKD),and the staging application strategy of"simultaneous treatment of the spleen and kidney".Based on this theory,it systematically reviews the role of Shanyao(Dioscoreae Rhizoma)in preventing and treating DKD.By consulting relevant classical TCM texts,this paper verifies numerous classic formulas containing Shanyao(Dioscoreae Rhizoma)for preventing and treating DKD,and systematically analyzes their compatibility,dosage,processing methods,administration methods,therapeutic efficacy,and indications.The systematic review reveals that Shanyao(Dioscoreae Rhizoma)highly aligns with the pathogenesis of spleen-kidney deficiency in DKD,making it an ideal herb for preventing and treating DKD under the guidance of the"simultaneous treatment of the spleen and kidney"theory.This paper provides a theoretical basis for the precise clinical application of Shanyao(Dioscoreae Rhizoma)in DKD management and for optimizing TCM prevention and treatment strategies for DKD.It also lays a foundation for future in-depth modern pharmacological and clinical research on Shanyao(Dioscoreae Rhizoma)in preventing and treating DKD.
张斯皓;俞赟丰;田娜;黄湘宁;喻嵘
湖南中医药大学第一附属医院,湖南 长沙 410007湖南中医药大学第一附属医院,湖南 长沙 410007湖南中医药大学第一附属医院,湖南 长沙 410007||湖南省人民医院(湖南师范大学附属第一医院),湖南 长沙 410000湖南中医药大学第一附属医院,湖南 长沙 410007湖南中医药大学,湖南 长沙 410208
医药卫生
糖尿病肾病脾肾同治山药消渴肾病
diabetic kidney diseasesimultaneous treatment of the spleen and kidneyShanyao(Dioscoreae Rhizoma)wasting thirst-kidney disease
《药食同源杂志》 2026 (4)
247-257,11
国家自然科学基金区域联合项目(U21A20411)湖南省自然科学基金创新研究群体项目(2024JJ1007)湖南中医药大学学科建设"揭榜挂帅"项目(22JBZ002).
评论