基于临床大语言模型的文本与结构化数据融合型急诊分诊预测模型研究OA
Clinical-large-language-based emergency triage prediction model incorporating text and structured data
目的:基于临床大语言模型,构建一种融合非结构化临床文本与结构化分诊信息的急诊分诊预测模型,用于急诊患者住院需求及危重结局的早期预测.方法:基于MIMIC-Ⅳ-ED数据库纳入成人急诊就诊记录,提取分诊阶段可获得的年龄、性别、6项生命体征(体温、心率、呼吸频率、血氧饱和度、收缩压和舒张压)及诊断文本信息.采用临床大语言模型ClinicalBERT对诊断文本进行语义特征编码,并与结构化分诊信息进行融合,构建预测模型ClinFusion.为评估ClinFusion模型的性能优势,在统一评估框架下与多种传统分诊工具及机器学习模型进行比较.结果:在住院需求预测任务中,ClinFusion模型的受试者工作特征曲线下面积(area under the receiver operating characteristic curve,AUROC)和精确率-召回率曲线下面积(area under the precision-recall curve,AUPRC)分别为0.896和0.885,均高于最优机器学习模型多层感知机(multi-layer perceptron,MLP)模型(AUROC和AUPRC分别为0.820和0.791),以及最优传统分诊工具急诊严重指数(emergency severity index,ESI)(AUROC和AUPRC分别为0.708和0.628).在危重结局预测任务中,ClinFusion模型的AUROC和AUPRC分别为0.915和0.541,均优于最优机器学习模型梯度提升模型(AUROC和AUPRC分别为0.881和0.398),以及最优传统分诊工具ESI(AUROC和AUPRC分别为0.806和0.199).结论:融合临床文本与分诊结构化信息的ClinFusion模型可显著提升急诊患者住院需求及危重结局的早期预测能力,为急诊智能分诊与临床决策支持提供了一种高效且可行的技术方案.
Objective To develop an emergency triage prediction model based on a clinical large language model by inte-grating unstructured clinical text with structured triage information,so as to facilitate the early prediction of hospitalization and critical outcomes in emergency department(ED)patients.Methods The diagnostic text information and data on age,gender and six vital signs were extracted based on the adult emergency department visit records from the MIMIC-Ⅳ-ED database,including body temperature,heart rate,respiratory rate,oxygen saturation,systolic blood pressure and diastolic blood pressure.The semantic features from the diagnostic texts were encoded with the ClinicalBERT large language model,and then integrated with the structured triage information to build a ClinFusion predictive model.The ClinFusion predictive model had its performance verified by the comparison with various traditional triage systems and machine learning models within a unified evaluation framework.Results In the hospitalization prediction task,the ClinFusion predictive model achieved an area under the receiver operating characteristic curve(AUROC)of 0.896 and an area under the precision-recall curve(AUPRC)of 0.885,outperforming the best-performing machine learning model of multilayer perceptron(MLP)with an AUROC of 0.820 and an AUPRC of 0.791 and the best-performing traditional triage system of emergency severity index(ESI)with an AUROC of 0.708 and an AUPRC of 0.628.In the critical outcome prediction task,the model achieved an AUROC of 0.915 and an AUPRC of 0.541,again outperforming the best-performing machine learning model of gradient boosting(GB)with an AUROC of 0.881 and an AUPRC of 0.398,and the best-performing traditional triage system of ESI with an AUROC of 0.806 and an AUPRC of 0.199.Conclusion The ClinFusion model integrating clinical text with structured triage data significantly improves the ability to predict emergency patients'need for hospitalization and critical outcomes at an early stage,offering an efficient and feasible technical solution for intelligent emergency triage and clinical decision support.[Chinese Medical Equipment Journal,2026,47(5):1-10]
徐小云;王楠;韩宝石;余明;赵艳梅;冯健;胡嘉参;刘斌;张广
军事科学院系统工程研究院,天津 300161武警特色医学中心,天津 300162解放军总医院第六医学中心,北京 100048军事科学院系统工程研究院,天津 300161天津大学卫生应急学院,天津 300072天津工业大学生命科学学院,天津 300387武警特色医学中心,天津 300162武警特色医学中心,天津 300162军事科学院系统工程研究院,天津 300161
医药卫生
急诊分诊大语言模型ClinicalBERT临床文本结构化数据自然语言处理
emergency triagelarge language modelClinicalBERTclinical textstructured datanatural language processing
《医疗卫生装备》 2026 (5)
1-10,10
天津市医学重点学科建设资助项目(TJYXZDXK-3-001D)
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