多区正向光学离焦眼镜对近视性屈光参差儿童的近视控制效果OA

Objective To compare the changes in refractive power and axial length(AL),as well as the changes in binocular anisometropia,in children with myopic anisometropia after one year of wearing defocus incorporated multiple seg-ments(DIMS)lenses versus single-vision(SV)lenses.Methods In this retrospective case study,children with myopic anisometropia[difference in spherical equivalent refraction(SER)between the two eyes ≥ 1.00 D]who were fitted with DIMS lenses(238 patients)or SV lenses(229 patients)at the Aier Eye Hospital Affiliated to Wuhan University from Octo-ber 2021 to August 2024 were enrolled as the DIMS group and the SV group.The patients,aged 6 to 14 years,had an SER ranging from-6.00 to-0.50 D and a cylindrical refractive error ≤4.00 D.Based on the refractive error and correction method,the eye with higher refractive error was defined as the high-power eye,while the eye with lower refractive error was defined as the low-power eye in both the DIMS and SV groups.According to the SER degree of the high-power eye,each group was further subdivided into a-0.50 to-3.00 D group and a-3.25 to-6.00 D group.Based on the degree of anisometropia,anisometropia of 1.00-1.88 D was classified as the low anisometropia group,and anisometropia of 2.00-4.00 D was classified as the high anisometropia group.The changes in SER,AL,and the differences in SER and AL between both eyes before and after one year of wearing the lenses were analyzed and compared among the groups.Results After one year of wearing lenses,compared with patients with high-power eyes in the SV group,patients with high-power eyes in the DIMS group showed slower changes in SER and AL;similarly,compared with patients with low-power eyes in the SV group,patients with low-power eyes in the DIMS group also showed slower changes in SER and AL.Intragroup comparison between the two eyes showed that the changes in SER and AL in patients with low-power eyes in the DIMS group were slo-wer than those in patients with high-power eyes in the DIMS group,and the differences were statistically significant(all P＜0.05).In the-0.50 to-3.00 D group and the-3.25 to-6.00 D group,the changes in SER and AL of patients with high-power and low-power eyes in the DIMS group were smaller than those of patients with the corresponding power in the SV group.In the-3.00 to-6.00 D group,the changes in SER and AL of patients with low-power eyes in the DIMS group were slower than those of patients with high-power eyes in the DIMS group,and the differences were statistically significant(all P＜0.05).In the low anisometropia group,the changes in SER and AL of patients with high-power and low-power eyes in the DIMS group were slower than those of patients with high-power and low-power eyes in the SV group.In the high aniso-metropia group,the changes in SER and AL of patients with low-power eyes in the DIMS group were slower than those of patients with low-power eyes in the SV group.The difference in AL after one year of wearing lenses was greater in patients wearing DIMS lenses than in those wearing SV lenses,and the differences were statistically significant(all P＜0.05).Conclu-sion Wearing DIMS lenses can effectively slow down the progression of refractive error and AL in both eyes of children with myopic anisometropia,and wearing DIMS lenses can also achieve better myopia control effects in children with low myopia and anisometropia.