BNCT束流整形体设计及其特性优化研究进展OA

Boron neutron capture therapy(BNCT)is an innovative radiation therapy capable of selectively targeting and destroying tumor cells.The beam shaping assembly(BSA),a critical core component of BNCT,plays an essential role in moderating fast neutrons,reducing radiation exposure to patients and healthcare providers,and optimizing dosimetric parameters.Based on numerical simulations and clinical trials conducted both domestically and internationally,this paper summarizes the structural design and theoretical foundations of the BSA in BNCT.It provides an in-depth discussion of the components within the BSA,including moderators,reflectors,thermal neutron absorbers,and gamma-ray shielding layers.Guided by the design parameters from the International Atomic Energy Agency(IAEA),this paper evaluates the design requirements for each component.The selection of materials for each component considers key influencing factors,such as fast neutron scattering cross-section,thermal neutron absorption cross-section,atomic mass,and material density.Finally,recent advances in the material and structural design of BSA systems specific to neutron sources are reviewed,offering insights into optimizing neutron source performance.