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基于脑-肠-微生物群轴探讨中药治疗失眠的作用OA

Treatment of Traditional Chinese Medicine Theory to Regulate Intestinal Flora Treatment Insomnia

中文摘要英文摘要

失眠是临床常见病,严重影响人们生活质量.近些年很多研究发现肠道菌群与失眠关系密切,出现大量关于调节脑-肠-微生物群轴治疗失眠的相关研究.肠道菌群及其代谢物与失眠有关,肠道菌群的紊乱会加重失眠.中医药在治疗失眠方面自古具有独特的优势.现以肠道菌群为靶点,以中医药为手段,为失眠的治疗带来新希望.文章以肠道菌群为切入点,以调节脑-肠-微生物群轴为思路,论述中医药与肠道菌群、肠道菌群与失眠的关系、脑-肠-微生物轴诱导失眠的机制、中医药调控肠道菌群在预防和治疗失眠中的作用机制,为临床治疗失眠提供新思路.

Insomnia is a common clinical disease,which seriously affects people's quality of life.In recent years,many schol-ars have found that the intestinal flora is closely related to insomnia,and a large number of research on regulating the brain-in-testinal-microbial group axis to treat insomnia.Studies have found that the intestinal flora and its metabolites are related to in-somnia,and the disorder of the intestinal flora will increase insomnia.Traditional Chinese medicine has unique advantages in the treatment of insomnia.Now take the intestinal flora as the target and the Chinese medicine as the means to bring new hope for the treatment of insomnia.This article takes the intestinal flora as the starting point,and the thinking of regulating the brain-intesti-nal-microbial group shaft,discuss the relationship between Chinese medicine and intestinal flora,intestinal flora and insomnia,brain-intestinal-microbial axis induction of insomnia mechanism,Chinese medicine regulates the mechanism of intestinal flora in preventing and treating insomnia,providing new ideas for clinical treatment of insomnia.

张涛;魏智;高鹏鹏

宁夏回族自治区中西医结合医院,宁夏银川75000宁夏回族自治区中西医结合医院,宁夏银川75000宁夏回族自治区中西医结合医院,宁夏银川75000

医药卫生

失眠中医药肠道菌群脑-肠-微生物轴

insomniaChinese medicineintestinal florabrain-intestinal-microbial axis

《实用中医内科杂志》 2026 (5)

26-29,4

国家中药管理局甘肃郑氏针法学术流派传承工作室建设项目(998399957).

10.13729/j.issn.1671-7813.Z20240774

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