桥本甲状腺炎中医证型相关性研究进展OA
Research Progress on the Correlation of Traditional Chinese Medicine Patterns in Hashimoto's Thyroiditis
综合近年来有关桥本甲状腺炎(Hashimoto's thyroiditis,HT)中医辨证分型的客观化研究,发现对HT的中医辨证分型与甲状腺功能及抗体指标、甲状腺超声特征、相关候选基因、蛋白组学等方面的相关性研究已经取得了很大的进展.HT属于本虚标实,虚实夹杂之证,其证型与相关的临床理化指标密切相关,临床常见中医证型早期多以肝郁气滞兼脾虚痰浊、湿热等实证为主,中晚期多累及脾肾阳虚夹瘀、痰、湿.但目前HT临床研究尚缺少国家标准化的中医辨证分型,认为应制定统一的中医辨证分型标准化,尤其通过结合现代医学客观化指标,形成较为一致的中医量化客观指标,更有利于推动和提高HT的规范化中医诊疗水平.
Objectivized studies on syndrome differentiation and classification of Hashimoto's thyroiditis(HT)in recent years are summarized.The results showed that much progress has been made in the study of the correlation between syndrome differen-tiation and classification of HT and thyroid function and antibody indexes,thyroid ultrasound features,related candidate genes,and proteomics.Clinically,this disease belongs to the pattern of deficiency in origin and excess in superficiality,intermingled deficiency and excess.The type of syndrome is closely related to the relevant clinical physical and chemical indicators.The com-mon syndrome types in the early stage are mainly characterized by liver depression and qi stagnation,spleen deficiency with phlegm turbidity,damp heat and other empirical manifestations.In the middle and late stages,it is mostly due to spleen kidney yang deficiency with blood stasis,phlegm,and dampness.However,clinical studies of HT currently lack a nationally standard-ized traditional Chinese medicine syndrome.Through the development of a unified standardization of Traditional Chinese Medi-cine syndrome,especially through the combination of modern medical objectification indicators to form a more consistent quantita-tive and objective indexes of traditional Chinese medicine.This is more conducive to promoting and improving standardized tradi-tional Chinese medicine diagnosis and treatment of HT.
杨正荣;韦茂英;暴雪丽;张文华;董陈露;张舒文
黔东南州中医医院,贵州凯里 556000北京中医药大学东直门医院,北京 100700北京中医药大学东直门医院,北京 100700北京中医药大学东直门医院,北京 100700北京中医药大学东直门医院,北京 100700北京中医药大学,北京 100029
医药卫生
桥本甲状腺炎中医证型相关性研究
Hashimoto's thyroiditistraditional Chinese medicine syndrome typescorrelation research
《实用中医内科杂志》 2026 (5)
5-7,3
国家资助博士后研究人员计划项目(GZC20230324)中国博士后科学基金面上项目(2024M750263)北京市高等教育学会立项面上课题项目(MS2024205)
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