成人隐匿性自身免疫性糖尿病微血管并发症研究进展OA

Latent autoimmune diabetes in adults(LADA)is a distinct subtype of autoimmune diabetes.This condition is characterized by an autoimmune-mediated progressive decline in β-cell function,with microvascular pathology exhibiting unique pathological progression and clinical features.The development and progression of microvascular complications in LADA patients are associated with various factors,including genotyping,autoimmune mechanisms,and biomarkers.Investigating the underlying mechanisms and clinical characteristics of LADA is of significant clinical importance for early identification of high-risk populations,formulating individualized intervention strategies,and delaying the progression of complications.This review consolidates recent research advances in the field of LADA-related microvascular complications,aiming to systematically elucidate the patterns of their development and progression.It seeks to provide theoretical support and clinical guidance for early risk prediction,personalized treatment,and improved patient outcomes.