首页|期刊导航|陕西中医药大学学报|基于"脾藏营,营舍意"探究胃癌术后芪黄煎剂调节肠黏膜免疫屏障与肠神经系统的中医内涵

基于"脾藏营,营舍意"探究胃癌术后芪黄煎剂调节肠黏膜免疫屏障与肠神经系统的中医内涵OA

Promotion of Intestinal Mucosal Immune Barrier and the Recovery of Enteric Nervous System by Astragalus Huang Decoction after Gastric Cancer Surgery Based on the Neijing"Spleen Hides Ying,Ying Sheds Meaning"

中文摘要英文摘要

从"脾藏营,营舍意"理论视角,探究胃癌术后芪黄煎剂促进肠黏膜免疫屏障与肠神经系统(enteric nervous system,ENS)恢复的中医内涵.胃癌术后肠神经系统紊乱,营养难以为继,肠黏膜免疫屏障损伤无法发挥"抵御外邪,未病先防"的作用.《内经》以"脾藏营,营舍意"说明了精纯柔和、赋予营养之"营"与统摄机体、监察外邪之"意"相辅相成的生理联系,通过阐述术后肠黏膜免疫屏障、ENS 的病变与"脾不藏营舍意"的联系,并分析脾"藏营舍意"理论与胃癌术后健脾通里之芪黄煎剂调节肠黏膜免疫屏障、恢复 ENS、分泌胃泌素调节肠液的相关性,认为芪黄煎剂引发的生物学变化符合"脾藏营舍意"理论.

From the perspective of the theory of"the spleen stores the ying,the ying sheds the meaning",we explore the Chinese connotation of Qi Huang decoction to promote the recovery of the intestinal mucosal immune barrier and the enteric nervous system(ENS)after gastric cancer surgery,which is characterized by disorders of the enteric nervous system,unsustainable nutrition,and the damage of the intestinal mucosal immune barrier that cannot play the role of"resisting external evils and preventing diseases before they occur".The damage to the immune barrier of the intestinal mucosa cannot play the role of"resisting external evils and preventing diseases before they occur".The"Internal Canon"explains the physiological connection between"Ying",which is pure and soft and gives nutrition,and"Yi",which regulates the body and monitors external evils,with"Spleen hides Ying and Ying sheds Yi",and this paper explains the physiological connection between the postoperative intestinal mucosal immune barrier and the"Yi",which regulates the body and monitors the external evils.This paper describes the connection between the postoperative intestinal mucosal immune barrier,ENS lesions and"spleen does not hide the Ying's intention",and analyzes the correlation between the theory of spleen's"hiding the Ying's intention"and the postoperative gastric cancer's postoperative Qi Huang Decoction which strengthens the spleen and passes through the liver to regulate the intestinal mucosal immune barrier,restore ENS,and secrete gastrin to regulate the intestinal fluids.It was concluded that the biological changes induced by the decoction of Qi Huang were in accordance with the theory of"the spleen hides the intention of the camps".In this paper,we organically combine the theory of spleen"hiding Ying She Yi"with modern molecular mechanism,enrich the theoretical connotation,broaden the field of application,and clarify the clinical value of astragalus huang decoction to improve the intestinal function by assisting the spleen"hiding Ying She Yi",and we hope that it will be used in the future to improve the intestinal function of spleen"hiding Ying She Yi".We hope to apply the theory of the spleen's"hiding the camps and the will"to the analysis of the pathogenesis and treatment of intestinal diseases after gastrectomy,and to provide new ideas for the study of the molecular mechanism of more prescriptions for strengthening the spleen and clearing up the bowels.

倪泽瑞;董宇昂;林峙豪;张冬阳;曹宇翔;方文凯;武洋;张珺;沈毅

安徽中医药大学第一临床医学院,安徽 合肥 230012安徽中医药大学第一临床医学院,安徽 合肥 230012安徽中医药大学第一临床医学院,安徽 合肥 230012安徽中医药大学第一临床医学院,安徽 合肥 230012安徽中医药大学第一临床医学院,安徽 合肥 230012安徽中医药大学第一临床医学院,安徽 合肥 230012安徽中医药大学第一临床医学院,安徽 合肥 230012安徽中医药大学中医学院,安徽 合肥 230012安徽中医药大学第一附属医院,安徽 合肥 230031

医药卫生

芪黄煎剂脾藏营,营舍意肠神经肠黏膜免疫屏障

astragalus huang decoctionspleen hides ying,ying shei yienteric nervous systemintestinal mucosal im-mune barrier

《陕西中医药大学学报》 2026 (3)

54-59,6

国家自然科学基金面上项目(82174160)2023年度安徽省高校自然科学研究重点项目(2023AH050752)

10.13424/j.cnki.jsctcm.2026.03.008

评论