经导管动脉硬化栓塞联合局部注射治疗口腔颌面部巨大血管瘤临床价值研究OA

Objective:To explore the clinical value of transcatheter arteriosclerotic embolization combined with local injection of absolute ethanol or lauromacrogol in the treatment of giant hemangiomas of the oral and maxillofa-cial region.Methods:A total of 168 patients with giant oral and maxillofacial hemangiomas were enrolled and divided into two groups according to the treatment plan:the combined treatment group(transcatheter arteriosclerotic emboli-zation combined with sequential ultrasound-guided absolute ethanol or lauromacrogol sclerotherapy,92 cases)and the simple embolization group(transcatheter arteriosclerotic embolization alone,76 cases).Baseline data,number of treatments,symptom relief time,tumor volume reduction rate,clinical efficacy,occurrence of complications and recur-rence were compared between the two groups.Results:There were no significant differences in baseline data such as age,gender,maximum tumor diameter,preoperative tumor volume,lesion location and hemodynamic classification between the combined treatment group and the simple embolization group(all P＞0.05).There was no significant difference in the number of embolization treatments between the two groups(P＞0.05).The relief time of pain and swelling in the combined treatment group was shorter than that in the simple embolization group(all P＜0.05).The tumor volume reduction rate of the combined treatment group at 1,3 and 6 months after treatment was higher than that of the simple embolization group(all P＜0.05).The total effective rate and marked effective rate of the com-bined treatment group were higher than those of the simple embolization group(all P＜0.05).There were no signifi-cant differences in the incidence of post-embolization syndrome,aggravated local swelling,transient numbness of nerves and total incidence of complications between the two groups(all P＞0.05).The recurrence rate of the com-bined treatment group was lower than that of the simple embolization group,but the difference was not statistically significant(P＞0.05).Conclusion:Transcatheter arteriosclerotic embolization combined with local injection of abso-lute ethanol or lauromacrogol has a good curative effect in the treatment of giant oral and maxillofacial hemangiomas.It can shrink the tumor faster,relieve symptoms,has a tendency to reduce long-term recurrence,and has high safety.