针刺联合艾灸治疗急性胰腺炎的疗效观察OA
Clinical observation on the efficacy of acupuncture combined with moxibustion in the treatment of acute pancreatitis
目的 观察针刺联合艾灸治疗急性胰腺炎(acute pancreatitis,AP)的临床疗效.方法 将 60 例符合诊断标准的 AP 患者随机分为治疗组和对照组,每组 30 例.对照组给予常规西医治疗,治疗组在对照组基础上加用针刺与艾灸治疗.比较两组腹痛缓解时间、首次排气与排便时间、住院时间.观察两组治疗前后血清 C反应蛋白(C-reactive protein,CRP)、白细胞介素-6(interleukin-6,IL-6)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、降钙素原(procalcitonin,PCT)、D-乳酸、淀粉酶和脂肪酶变化,并比较两组临床疗效.结果 治疗组腹痛缓解时间、胃肠功能恢复时间(首次排气/排便)和住院时间均优于对照组(P<0.05).两组治疗后血清炎症因子(CRP、IL-6、TNF-α)水平均较治疗前降低(P<0.05),且治疗组低于对照组(P<0.05);两组治疗后血清 PCT、乳酸、淀粉酶及脂肪酶水平均较治疗前降低(P<0.05),且治疗组低于对照组(P<0.05).治疗组总有效率为 93.3%,显著高于对照组的 73.3%,差异具有统计学意义(P<0.05).结论 在常规西医治疗基础上,针刺联合艾灸早期干预 AP 安全有效,能显著改善临床症状,抑制炎症反应,促进胃肠功能恢复.
Objective To observe the clinical efficacy of acupuncture combined with moxibustion in the treatment of acute pancreatitis(AP).Method Sixty patients with acute pancreatitis who met the diagnostic criteria were randomly divided into a treatment group and a control group,with 30 cases in each group.The control group received conventional Western medical treatment,while the treatment group received acupuncture combined with moxibustion in addition to the same conventional treatment.The time to pain relief,time to first flatus and defecation,and length of hospital stay were compared between the two groups.Changes in serum levels of C-reactive protein(CRP),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),procalcitonin(PCT),D-lactate,amylase,and lipase before and after treatment were observed,and overall clinical efficacy was compared between the two groups.Result The treatment group showed significantly shorter time to abdominal pain relief,faster recovery of gastrointestinal function(earlier first flatus and defecation),and shorter hospital stay compared with the control group(P<0.05).After treatment,serum levels of inflammatory markers(CRP,IL-6,and TNF-α)decreased in both groups compared with baseline(P<0.05),with significantly lower levels in the treatment group than in the control group(P<0.05).Serum levels of PCT,D-lactate,amylase,and lipase were also reduced in both groups after treatment(P<0.05),and the reductions were more pronounced in the treatment group(P<0.05).The total effective rate in the treatment group was 93.3%,which was significantly higher than that in the control group(73.3%)(P<0.05).Conclusion On the basis of conventional Western medical treatment,early intervention with acupuncture combined with moxibustion is safe and effective for the treatment of acute pancreatitis.This combined therapy can significantly alleviate clinical symptoms,suppress inflammatory responses,and promote the recovery of gastrointestinal function.
安鹏;俞振飞
杭州市中医院丁桥院区,杭州 310000杭州市中医院丁桥院区,杭州 310000
医药卫生
针灸疗法灸法温和灸艾条灸胰腺炎炎症因子胃肠功能
Acupuncture moxibustion therapyMoxibustionMild moxibustionMoxa-stick moxibustionAcute pancreatitisInflammatory factorsGastrointestinal function
《上海针灸杂志》 2026 (5)
497-501,5
浙江省中医药科技计划项目(2024ZL660)
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