何泽云教授自拟桂芪冬肾丸联合中药贴敷治疗慢性肾脏病经验OA
Professor He Zeyun's experience in treating chronic kidney disease with self-formulated Guiqi Dongshen Pills combined with Chinese herbal patch application
慢性肾脏病(CKD)是由多种病因导致的肾脏结构或功能异常持续≥3个月的临床综合征,具有起病隐匿、病程迁延、预后不良等特点,最终可进展为终末期肾脏病(ESRD).ESRD治疗手段有限,主要依赖肾脏替代治疗(包括肾脏移植、血液或腹膜透析),不仅给患者带来巨大痛苦,也造成沉重的家庭和社会负担.随着人口老龄化进程加速,全球CKD患病率持续攀升,其相关病死率在死因顺位中逐年上升.我国CKD患病以早期阶段为主,通过规范治疗可有效延缓病情进展,改善患者预后.何泽云教授长期致力于CKD的临床与科研工作,认为CKD主要病机为脾肾虚损,三焦气化功能失调,水液代谢障碍,湿浊久蕴不化则郁而化热,热邪与肾络中的有形实邪相结,形成肾络癥瘕,致使气血运行不畅,病理产物蓄积成毒.治疗上使用自拟桂芪冬肾丸联合穴位贴敷,既温肾健脾补肺,又利湿化瘀解毒,从而使肺脾肾同补,湿瘀毒同泄,达到治疗CKD的目的.
Chronic kidney disease(CKD)is a clinical syndrome characterized by abnormalities in kidney structure or function persisting for≥3 months due to various etiologies.It features an insidious onset,prolonged course and poor progno-sis,ultimately progressing to end-stage renal disease(ESRD).Treatment options for ESRD are limited,primarily relying on renal replacement therapy(including kidney transplantation,hemodialysis or peritoneal dialysis),which imposes sig-nificant suffering on patients and a heavy burden on families and society.With the acceleration of population aging,the global prevalence of CKD continues to rise,and its associated mortality rate is increasing annually in cause-of-death rank-ings.In China,CKD is predominantly in its early stages,and standardized treatment can effectively delay disease progres-sion and improve patient prognosis.Professor He Zeyun has long been dedicated to the clinical and scientific research of CKD.He posits that the main pathogenesis of CKD involves deficiency and impairment of the spleen and kidney,dysfunc-tion of the triple energizer Qi-transformation,and disturbance in water metabolism.Lingering dampness-turbidity,if unre-solved,becomes stagnant and transforms into heat.This heat pathogen then combines with tangible pathogens in the kidney collaterals,forming concretions and accumulations(zheng jia),leading to impeded Qi and blood circulation and the accu-mulation of pathological products into toxins.Therapeutically,he employs self-formulated Guiqi Dongshen Pills combined with acupoint application.This approach simultaneously warms the kidney,fortifies the spleen,supplements the lung,drains dampness,resolves stasis and removes toxins.Thereby,it tonifies the lung,spleen,and kidney concurrently and drains dampness,stasis and toxins simultaneously,achieving the goal of treating CKD.
周琳;何泽云;彭亚军
湖南中医药大学第一附属医院,湖南 长沙 410007湖南中医药大学第一附属医院肾脏内科,湖南 长沙 410007湖南中医药大学第一附属医院肾脏内科,湖南 长沙 410007
医药卫生
慢性肾脏病桂芪冬肾丸中药贴敷
CKDGuiqi Dongshen PillsChinese herbal patch application
《山西中医药大学学报》 2026 (4)
390-395,6
湖南省自然科学基金(2023JJ30473)湖南省级中医重点专科(czxm-sbk-2023001)
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