薄层色谱一标多测方法在逍遥丸中的应用OA

Objective:To establish a thin-layer chromatography with one standard and multiple measurement method for the identification of multiple medicinal materials in Xiaoyao Pills,aiming to control the quality of Chinese patent medi-cine while improving testing efficiency and reducing costs.Methods:Based on the characteristics of components present in different medicinal materials in Xiaoyao Pills,the experiment was carried out by optimizing the preparation method of the test solution,developing the system,and screening different chromogenic agents.One chromatographic system was devel-oped for the simultaneous identification of Danggui and Baizhu,while another system was developed for the simultaneous identification of Baishao and Gancao,thereby establishing a thin-layer chromatography with one standard and multiple measurement method.Results:The thin-layer chromatography spots were clear with good separation and appropriate reten-tion factor(Rf)values.The method demonstrated satisfactory specificity,repeatability and durability.Conclusion:The thin-layer chromatography with one standard and multiple measurement method is scientific,rational,simple and rapid.It can effectively improve testing efficiency and provides a new approach for the identification of Chinese herba preparations con-taining Danggui,Baiazhu,Baishao and Gancao.