饮水添加25-羟基维生素D3复合物对商品肉鸡生产性能、免疫应答及血液生化指标的影响OA

This study aimed to evaluate the effects of supplementing 25-hydroxyvitamin D3 complex in drinking wa-ter on the growth performance,immune antibody levels,and blood biochemical parameters of commercial broilers.Two environmentally consistent chicken houses were selected,each housing 31,000 broilers of the 308 breed.The experi-mental group received 25-hydroxyvitamin D3 complex in their drinking water(100 mL per 100 kg of water),while the control group did not.The results showed that the average slaughter weight in the experimental group(2 657 g/bird)was 50 g higher than that in the control group(2 607 g/bird).The feed conversion ratio(1.573)was lower than that of the control group(1.582),and the cumulative mortality rate decreased by 1.12%.The serum 25-OH-D3 concentration in the experimental group(97.94 ng/mL)was significantly higher than that in the control group(76.24 ng/mL)(P<0.05).The ND antibody titer(4.87)was significantly higher than that of the control group(3.00)(P<0.05),while no signifi-cant difference was observed in the H9N2 antibody titers between the two groups.The experimental group showed sig-nificantly increased serum calcium and phosphorus concentrations and calcium-phosphorus product(P<0.05),significantly reduced amylase and creatinine levels(P<0.05),and significantly increased albumin/globulin ratio and AST/ALT ratio(P<0.05).In conclusion,the addition of 25-hydroxyvitamin D3 complex to drinking water can significantly improve cal-cium and phosphorus metabolism,enhance the immune response to Newcastle disease vaccines,and improve growth performance in broilers,demonstrating promising application potential in large-scale broiler production.