窄谱成像放大内镜联合色素内镜与单一窄谱成像放大内镜在结直肠早期肿瘤检查中的应用对比研究OA

Objective:To conduct a self-controlled study on the diagnostic efficacy of magnifying endoscopy with narrow-band imaging(ME-NBI)combined with chromoendos-copy(CE)compared with ME-NBI alone in the detection and diagnosis of early colorectal tumors.Methods:A total of 232 early colorectal lesions identified via colonoscopy at Qingbaijiang District People's Hospital of Chengdu between July 2023 and July 2024 were included in this study.All lesions were evaluated by ME-NBI alone(ME-NBI group)and ME-NBI com-bined with CE(combined group).The pathological findings were used as the gold standard to evaluate the diagnostic per-formance of the two groups.Results:There was no significant difference between the two groups in diagnostic accuracy for lesions of different sizes(P>0.05).Pit pattern classification showed good agreement with pathological diagnosis in both the combined group and the ME-NBI group(Kappa values:0.783 and 0.758,P<0.05).Satisfactory agreement was also ob-served for the diagnosis of high-risk early neoplastic lesions(Kappa=0.893,P<0.05).The diagnostic sensitivity was 92.5%for both groups.The specificity was 78.4%for the combined group and 75.3%for the ME-NBI group.The positive predictive values were 96.9%and 95.6%,and the negative predictive values were 85.3%and 82.8%,respectively.The accuracy was 92.2%for the combined group and 91.4%for the ME-NBI group(all P>0.05).Conclusion:The two groups demonstrated largely consistent diagnostic accuracy.In the examination of early colorectal tumors,ME-NBI can serve as the cornerstone,while challenging cases may require its combination with CE.