面部色素性扁平苔藓1例OA

We report a case of facial lichen planus pigmentosus.A 54-year-old female com-plained of brown spots on her face for two months.Two months ago,the patient developed a large pale erythema on her forehead and cheeks of unknown cause,characterized by unclear boundaries and mild itching.The pale erythema gradually transformed into large dark brown spots.A derma-tological examination revealed diffuse patchy brown spots on the forehead and cheeks,some of which had a reticular appearance and unclear boundaries.Confocal laser scanning microscopy showed focal thickening of the granular layer,irregular thickening of the spinous layer,liquefac-tion degeneration of the basal layer,and infiltration of phagocytic and inflammatory cells in the su-perficial and papillary layers of the dermis.Pathological results indicated hyperkeratosis,wedge-shaped thickening of the granular layer,thickening and edema of the spinous layer,a few colloid bodies beneath the epidermis,liquefaction degeneration of the basal layer,and inflammatory infil-tration of lymphocytes,phagocytes,and a few histiocytes in the dermal papillary layer.The diag-nosis was facial lichen planus pigmentosus.The patient was treated with 75 mg of oral cyclosporine soft capsules twice daily,an intramuscular injection of 1 mL of compound betamethasone once,and topical 0.03％tacrolimus ointment to be applied at bedtime for one month.The patient has lost to follow-up.